Brodalumab Effective for Psoriasis Treatment After Other IL-17 RA Failure
The short- and long-term effectiveness of brodalumab in patients with psoriasis in whom treatment with IL-17A inhibitors has failed is examined.
Diagnosis & Disease Information
Risk Factors Associated With Vertical Transmission in Mothers With HIV Infection
Researchers sought to assess whether there is an association between maternal HIV drug resistance and an increased risk for vertical transmission and to describe the dynamics of drug resistance in infants with HIV infection.
Clinical Efficacy, Safety of Janus Kinase Inhibitors in Patients Hospitalized With COVID-19
Investigators conducted a meta-analysis of 3 randomized controlled trials that compared the clinical safety and efficacy of janus kinase inhibitors with placebo or standard care for the treatment of patients with COVID-19.
The Changing Guidelines on the Role of MRI in Multiple Sclerosis Management
The 2021 MAGNIMS-CMSC-NAIMS provided updated consensus recommendations on MRI use in the management of multiple sclerosis.
Cytisine vs Varenicline for Smoking Cessation: Results From a Noninferiority Trial
The researchers wanted to know if standard cytisine treatment for 25 days was at least as effective for smoking cessation as standard varenicline treatment for 84 days.
Can the Genetic Overlap of ADHD and Autism Guide Better Treatment?
Study researchers investigated the genetic overlap between ADHD and autism to determine if shared gene variants may provide insight into treatment targets.
Obstructive Sleep Apnea Raises the Risk of Sudden Cardiac Death
We interview experts Younghoon Kwon, MD, MS, FACC, and Richard J Castriotta, MD, FCCP, FAASM, about the connections between obstructive sleep apnea-sudden cardiac death.
Virgin Coconut Oil May Prevent Damaged Skin from Hand Sanitizer Overuse
The utility of virgin coconut oil as a natural agent to counteract the adverse effects of alcohol-based hand sanitizers during COVID-19 is assessed.
First Alzheimer Disease Prevention Trial Using Amyloid-Targeting Drugs Gantenerumab or Solanezumab
The researchers conducted a randomized, placebo-controlled, multi-arm trial of gantenerumab or solanezumab in participants with dominantly inherited Alzheimer disease across asymptomatic and symptomatic disease stages.
Post-Traumatic Coma Prognosis is Difficult to Predict
Bianciardi and colleagues investigated the patterns of microbleeds associated with post-traumatic coma and the recovery of consciousness in young comatose patients.
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