Pediatric Patients With Cardiovascular Disease Receive Multiple Off-Label Drugs
Researchers assessed the off-label use of cardiovascular medications in a home therapy setting for children with congenital or acquired heart disease.
Treatments
Lithium Did Not Reduce Suicide-Related Events Among Veterans With a History of Suicidality
In this study, patients were stratified by condition and suicide history and randomized to receive 600 mg/d extended-release lithium carbonate or placebo in addition to usual care.
Metformin and Sulfonylurea Use in People With Type 2 Diabetes and COVID-19
COVID-19 can cause additional complications and even death in people with a pre-existing conditions like type 2 diabetes. Researchers studied whether the medications people with type 2 diabetes often take were associated with a risk of dying from the virus.
RBX2660 Reduces Recurrent C difficile Infections in Patients With Comorbid Conditions
Researchers evaluated the safety and efficacy of the investigational, microbiota-based, live biotherapeutic RBX2660 for treatment of recurrent C difficile infection.
Pathogenic Effects of Probiotics in Children With Acute Gastroenteritis
Researchers conducted a study that compared the effects of probiotics vs placebo for the treatment of children with diarrhea secondary to acute gastroenteritis.
Nasal Spray With Iota-Carrageenan Decreases Risk for COVID-19 in Exposed Healthcare Workers
Investigators conducted a study to determine whether iota-carrageenan nasal spray decreases the risk for SARS-CoV-2 infection among health care workers managing patients with COVID-19.
Oral and Topical Antifungals Beneficial for Dupilumab Facial Redness in Atopic Dermatitis
A novel study reports the positive response to oral and topical antifungals for patients with atopic dermatitis (AD) treated with dupilumab who developed facial redness.
Brodalumab Effective for Psoriasis Treatment After Other IL-17 RA Failure
The short- and long-term effectiveness of brodalumab in patients with psoriasis in whom treatment with IL-17A inhibitors has failed is examined.
Risk Factors Associated With Vertical Transmission in Mothers With HIV Infection
Researchers sought to assess whether there is an association between maternal HIV drug resistance and an increased risk for vertical transmission and to describe the dynamics of drug resistance in infants with HIV infection.
Clinical Efficacy, Safety of Janus Kinase Inhibitors in Patients Hospitalized With COVID-19
Investigators conducted a meta-analysis of 3 randomized controlled trials that compared the clinical safety and efficacy of janus kinase inhibitors with placebo or standard care for the treatment of patients with COVID-19.
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