Groundwater Constituents May Increase the Risk of Kidney Cancer
An analysis of groundwater revealed 7 constituents — such as chlordane, dieldrin, and glyphosphate — that may increase the risk of kidney cancer.
Diagnosis & Disease Information
Cancer Patients With Diabetes May Have Worse Outcomes on ICIs
Cancer patients with type 2 diabetes may have worse survival outcomes on immune checkpoint inhibitor therapy, a new study suggests.
Exercise, Physical Activity Beneficial Among Patients With Kidney Cancer
In a study of patients who had ever been diagnosed with kidney cancer, those who reported exercise or physical activity in the past 30 days had reduced likelihood of reporting worse physical and mental health.
Live Bacterial Product Improves Outcomes in Metastatic Renal Cell Carcinoma
CBM588, a live bacterial product, improves the efficacy of first-line treatment with nivolumab and ipilimumab in patients with metastatic renal cell carcinoma, a study suggests.
Bevacizumab Biosimilar Vegzelma Gets FDA Approval
Vegzelma is a vascular endothelial growth factor inhibitor.
Trial Evaluating Nivolumab Plus Ipilimumab for Localized RCC Misses Endpoint
The CheckMate -914 trial included patients with localized RCC who underwent radical or partial nephrectomy and who were at high risk of relapse.
Allogeneic CAR T-Cell Candidate Fast Tracked for Renal Cell Carcinoma
The investigational product targets CD70, which is highly expressed in renal cell carcinoma with limited normal tissue expression.
HLA Variant May Predict Poor Outcomes of Immunotherapy in Cancer Patients
HLA-A*03 was associated with worse progression-free and overall survival.
Can Quality of Life Assessments Predict PFS, OS Across Cancer Types?
Recent studies showed associations between quality of life scores and survival in lung and prostate cancer as well as renal cell carcinoma.
FDA to Review Pembrolizumab for Additional Kidney, Endometrial Cancer Indications
The sBLA submissions are supported by data from the phase 3 KEYNOTE-564 trial and the phase 2 KEYNOTE-158 trial.
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