In this analysis, the children who had 1 or both parents with schizophrenia or bipolar disorder were matched with children without familial high risk for psychosis.
Seena Fazel of the University of Oxford, UK, and colleagues at the Karolinska Institute in Sweden compared the medicated and non-medicated periods of over 1.4 million beta blocker users.
The approval was based on data from adequate and well-controlled studies with risperidone long-acting injection (intramuscular).
Patients with acute appendicitis between 2000 and 2020 were evaluated for complications on the basis of having a mental health diagnosis.
The NDA is supported by data from a phase 1/2 trial that compared the investigational aripiprazole 2-month, long-acting injectable to aripiprazole 1-month depot.
Researchers investigated whether high-potency cannabis may be associated with a higher risk of psychosis and cannabis use disorder compared with lower-potency products.
The phase 3 EMERGENT-2 trial included 252 patients with schizophrenia who were experiencing symptoms of psychosis.
Although not bound by the committee’s recommendations, the Agency does take them into consideration when making decisions on approval.
Virtual reality has been explored as an adjunct to cognitive behavioral therapy, but little is known about how well it delivers automated therapy. To find out, the researchers conducted a clinical trial using 9 National Health Service trusts in England.
The approval was based on data from the phase 3 SERENITY I and II studies that evaluated Igalmi for the acute treatment of agitation associated with schizophrenia and bipolar disorders I and II, respectively.
