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Neurologic Disorders

Migraine Attacks Increase Following Stress

Migraine Attacks Increase Following Stress “Let-Down”

Migraine sufferers who experienced reduced stress from one day to the next are at significantly increased risk of migraine onset on the subsequent day, according to a new study conducted by researchers at the Montefiore Headache Center and Albert Einstein College of Medicine at Yeshiva University. Stress has long been believed to be a common headache trigger. In this study, researchers found that relaxation following heightened stress was an even more significant trigger for migraine attacks. Findings may aid in recommending preventive treatments and behavioral interventions. The study was published online today in Neurology, the medical journal of the American Academy of Neurology.

Fregoli Syndrome

Murder, Intrigue, and a Case Involving Fregoli Syndrome?

On January 26, 1996, the Newtown, PA police and 3 SWAT teams surrounded the du Pont mansion on the Foxcatcher estate, about 15 miles west of Philadelphia. Earlier that day, John du Pont, the chemical company heir, shot and killed his longtime friend, Dave Schultz, 36, an Olympic gold medalist in freestyle wrestling. Armed with several guns, du Pont refused to surrender to police and held up in his mansion. A standoff commenced. It was particularly cold, and after 2 days, the police shut off the power and heat. When Mr. du Pont went outside to investigate, they captured him.

Hereditary Sensory and Autonomic Neuropathy Type I and Type II

Born Painless (HSAN II and III)

Unlike hereditary sensory and autonomic neuropathy type I (HSAN I), HSAN II and HSAN III are inherited in an autosomal recessive pattern. Both conditions are characterized by a deficit in distal sensory perception, with the lower limbs more severely affected than the upper limbs. Touch and temperature perception are affected to varying degrees in these individuals, with some depressed deep tendon reflexes. However, their ability to sense vibration may be normal. The extent of autonomic neuropathy and dysfunction varies greatly between types II and III. Type III is more severe, not only in sensory manifestations but also to the degree in which the autonomic system is affected.



The word “trepanation” is Greek in origin (trypanon). It means “to bore.”

Trepanation was practiced worldwide prior to the advancements of brain surgery over the past century. It is a procedure where holes are drilled into a patient’s head, with the only precaution being that care is taken to avoid penetrating below the bone membrane in most cases, if you can imagine. It is one of the oldest surgical procedures on record, dating back to the time of the caveman.

Hereditary Sensory and Autonomic Neuropathy

Born Painless (HSAN I)

We all experience some form of physical pain in our lifetimes. Pain doesn’t discriminate; it is a universal quality that is easy to recognize. Pain is a powerful learning tool. B.F. Skinner, the father of operant conditioning (instrumental learning), demonstrated how behavior can be modified through positive and negative reinforcement (pain and pleasure). As most parents can attest, this type of learning may display rapid results. An everyday example of this is when a parent buys a child a toy to stop them from crying or whining. Although this may stop the crying/whining, it has the opposite effect on the child. The child learns that if they repeat that negative behavior, they will get what they want. Unfortunately, by rewarding undesired behavior, the habit can be difficult to break.

Month of Birth Impacts on Immune System Development

Month of Birth Impacts on Immune System Development

Newborn babies’ immune system development and levels of vitamin D have been found to vary according to their month of birth, according to new research.

The research, from scientists at Queen Mary, University of London and the University of Oxford, provides a potential biological basis as to why an individual’s risk of developing the neurological condition multiple sclerosis (MS) is influenced by their month of birth. It also supports the need for further research into the potential benefits of vitamin D supplementation during pregnancy.

Wilson's Disease

Wilson’s Disease

At age 24, a young woman (let’s call her Ann) was healthy, vibrant, and carefree. After her 25th birthday, Ann began to experience upper limb tremors. Within 4 months, the tremors progressed to all of Ann’s limbs, followed by bouts of mania. Due to the neuropsychological presentations, a psychiatrist prescribed Ann haloperidol, chlorpromazine, and propranolol to treat the mania. A further regimen of levodopa and carbidopa was prescribed by a neurophysician to treat the atypical Parkinson’s.

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