Tymlos Label Update Highlights Bone Building Mechanism of Action
The update is based on data from an open-label, single-arm histomorphometry study.
Diagnosis & Disease Information
Osteoporosis Treatments Compared to Assess Effects on Bone Mineral Density
The network meta-analysis compared the effects of 9 osteoporosis drugs on BMD.
FDA: New Warnings and Limitations Set for Certain JAK Inhibitors
The revisions are based on a completed review of a large randomized safety clinical trial, which included 4362 patients with rheumatoid arthritis.
Oral Myosin Inhibitor Fast Tracked for Becker Muscular Dystrophy
EDG-5506 is a selective, small molecule myosin inhibitor designed to protect injury-susceptible fast skeletal muscle fibers.
Botox Approval Expanded to Include 8 New Muscles for Upper Limb Spasticity
The indication for adult upper limb spasticity treatment now includes elbow and forearm muscles, intrinsic hand muscles, and thumb muscles.
Risk of Muscle Problems Based on Statin Therapy Intensity Investigated
Small increases in the risk for statin-associated muscle symptoms were observed for patients on high-intensity therapy.
Mindfulness Programs Appear to Improve Emotional Distress Symptoms Among Patients With Rheumatic Disease
Researchers compared the effectiveness of full-length vs brief mindfulness training programs for improving anxiety among patients with rheumatic disease.
Apitegromab Fast Tracked for Spinal Muscular Atrophy
Apitegromab is a selective inhibitor of the inactive form of myostatin to block its activation in the muscle.
Losmapimod Fast Tracked for Facioscapulohumeral Muscular Dystrophy
Losmapimod is a selective p38α/β mitogen activated protein kinase inhibitor that works by reducing the expression of the DUX4 gene in muscle cells.
Lockdown Tied to Worsening of Musculoskeletal Conditions
About half of U.K. patients experienced an increase in symptoms during early stages of the pandemic
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