5-ARIs Linked With Depression, But Not Suicide Risk
This Swedish population-based study has the largest sample size to date exploring these associations.
Diagnosis & Disease Information
Hepatitis C Guideline Updated for Chronic Kidney Disease Population
The update reflects advances in hepatitis C management, such as antiviral therapy, increased use of hepatitis C kidney grafts, and treatment of glomerular diseases associated with the virus.
Resistant Hypertension Effectively Treated With Novel Drug
Blocking the endothelin pathway could represent a new mode of action to lower blood pressure in resistant hypertension, according to investigators.
Continuing ACE Inhibitors Despite Potassium Change Can Have Benefits
Stopping renin-angiotensin-aldosterone inhibitors after hyperkalemia may offset their potential clinical benefits, according to investigators.
Apixaban Tied to Lower Risk of Gastrointestinal Bleeding
Findings were consistent for patients aged 80 years or older and patients with chronic kidney disease, who are often underrepresented in clinical trials.
Kidney Function Declines More Slowly With SGLT2 Inhibitor
Treatment with an SGLT2 inhibitor may help patients with CKD or type 2 diabetes better preserve their kidney function.
Finerenone May Protect Against Pneumonia and COVID-19
Finerenone, a mineralocorticoid receptor antagonist, may exert anti-inflammatory and anti-fibrotic effects, according to investigators.
COVID-19 Vaccines Reduce Risk of Severe Outcomes in CKD
Vaccination decreased the risk for COVID-related hospitalization and death, according to a retrospective study.
Paxlovid Use for COVID-19 May Be Feasible in Advanced CKD
Nirmatrelvir/ritonavir is not current recommended for patients with CKD stage 4 or 5, but low-dose regimens could avoid adverse events, according to the authors of a recent editorial.
Excessive Body Weight Lessens the Efficacy of Vitamin D Supplements
A round up of studies suggests it is difficult to increase serum total 25-hydroxyvitamin D levels enough to effectively lower elevated parathyroid hormone (PTH) levels in overweight patients with chronic kidney disease.
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