The Food and Drug Administration (FDA) has granted accelerated approval to Lumakras (sotorasib) for the treatment of adults with KRAS G12C-mutated locally advanced or metastatic non-small cell lung cancer (NSCLC), as determined by an FDA-approved test, who have received at least 1 prior systemic therapy. Sotorasib, an inhibitor of the RAS GTPase family, works by…
The approval was based on data from the phase 1 CHRYSALIS trial that evaluated Rybrevant in 81 patients with locally advanced or metastatic NSCLC with EGFR exon 20 insertion mutations whose disease had progressed on or after platinum-based chemotherapy.
An overview of the impact the updated USPSTF Lung Cancer Screening Guidelines will have on diagnosis and survival of lung cancer.
Oncologists and patients should be aware of the potential manifestations of the COVID-19 vaccination on imaging and the consequences this might have on disease assessment, treatment monitoring, and decision-making.
Aspirin, metformin, and statins were independently associated with decreased lung cancer mortality, according to a population-based study.
Current low-intensity smokers have an increased risk for respiratory and lung cancer mortality.
In the midst of the COVID-19 pandemic, patients with lung cancer face an increased risk of disease progression, reduced survival, and worse quality of life associated with delayed treatment.
A study of clinical trials found no evidence of bias in the reporting of clinical trials supported by pharmaceutical companies compared with studies that had other funding sources.
The USPSTF recommends annual low-dose computed tomography screening for people aged 50 to 80 years at high lung cancer risk due to smoking history.
Black and Hispanic patients are less likely to undergo guideline-recommended imaging at diagnosis of non-small cell lung cancer.
