USPSTF Issues Final Recommendations on Statin Use for Primary Prevention of CVD
These recommendations apply only to individuals without a history of CVD and who are not already taking statins.
Hyperlipoproteinemias
Evinacumab Cuts LDL-C in Children With Homozygous Familial Hypercholesterolemia
Evinacumab is a fully-human monoclonal antibody that binds to and blocks the function of angiopoietin-like 3
Pfizer Ends Development of Vupanorsen Over Disappointing Results, Safety Issues
The decision was made based on data from a phase 2b study that evaluated vupanorsen in statin-treated patients with dyslipidemia.
Leqvio Approved as Twice-Yearly Injection to Lower LDL-C in High-Risk Patients
The approval was based on data from the ORION-9, ORION-10, and ORION-11 trials that evaluated Leqvio in patients 18 years of age and older with HeFH or clinical ASCVD.
Statin Use Linked to Reduced Death Risk in Hospitalized COVID-19 Patients
Study authors analyzed data from 10,541 hospitalized patients with active COVID-19 disease to evaluate the relationship between the use of statins and COVID-19 outcomes.
Cholesterol Management Supplement Found to Contain Undeclared Rx Ingredient
Cholestene, a dietary supplement marketed for cholesterol management, has been found to contain a hidden drug ingredient, according to the Food and Drug Administration. Based on laboratory analysis, the product, which is sold on various websites and in some retail stores, has been found to contain lovastatin, an HMG-CoA reductase inhibitor (statin). Consuming a supplement…
Risk of Muscle Problems Based on Statin Therapy Intensity Investigated
Small increases in the risk for statin-associated muscle symptoms were observed for patients on high-intensity therapy.
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