Olezarsen Fast Tracked for Familial Chylomicronemia Syndrome
Olezarsen is an investigational LICA antisense medication designed to inhibit the production of apoC-III for patients at risk of disease due to elevated triglyceride levels.
Diagnosis & Disease Information
Evinacumab Under Review for Pediatric Homozygous Familial Hypercholesterolemia
Evinacumab is a fully-human monoclonal antibody that binds to and blocks the function of angiopoietin-like 3.
Low-Dose Statin Bests Six Commonly Used Cholesterol Health Supplements
The study included adults aged 40 to 75 years with no history of cardiovascular disease, an LDL-C of 70-189 mg/dL, and a 5-20% 10-year risk of ASCVD.
USPSTF Issues Final Recommendations on Statin Use for Primary Prevention of CVD
These recommendations apply only to individuals without a history of CVD and who are not already taking statins.
Evinacumab Cuts LDL-C in Children With Homozygous Familial Hypercholesterolemia
Evinacumab is a fully-human monoclonal antibody that binds to and blocks the function of angiopoietin-like 3
Pfizer Ends Development of Vupanorsen Over Disappointing Results, Safety Issues
The decision was made based on data from a phase 2b study that evaluated vupanorsen in statin-treated patients with dyslipidemia.
Leqvio Approved as Twice-Yearly Injection to Lower LDL-C in High-Risk Patients
The approval was based on data from the ORION-9, ORION-10, and ORION-11 trials that evaluated Leqvio in patients 18 years of age and older with HeFH or clinical ASCVD.
Statin Use Linked to Reduced Death Risk in Hospitalized COVID-19 Patients
Study authors analyzed data from 10,541 hospitalized patients with active COVID-19 disease to evaluate the relationship between the use of statins and COVID-19 outcomes.
Cholesterol Management Supplement Found to Contain Undeclared Rx Ingredient
Cholestene, a dietary supplement marketed for cholesterol management, has been found to contain a hidden drug ingredient, according to the Food and Drug Administration. Based on laboratory analysis, the product, which is sold on various websites and in some retail stores, has been found to contain lovastatin, an HMG-CoA reductase inhibitor (statin). Consuming a supplement…
Risk of Muscle Problems Based on Statin Therapy Intensity Investigated
Small increases in the risk for statin-associated muscle symptoms were observed for patients on high-intensity therapy.
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