Treatment for Accelerating Postop Bowel Function Gets Fast Track Status
LB1148 is a broad-spectrum serine protease inhibitor designed to neutralize digestive enzymes and potentially reduce intestinal damage.
Gastroenterology
Novel GI-Selective Therapy Gets Orphan Drug Designation for Pouchitis
The designation is supported by data from the 12-week, randomized, double-blind phase 2 FILLMORE trial.
Vemlidy Approved for Pediatric Patients With Chronic HBV Infection
The approval was supported by data from a phase 2 trial that included 70 patients aged 12 to less than 18 years with chronic HBV infection.
Mixed Results for Benralizumab in Eosinophilic Esophagitis Trial
The MESSINA study included patients 12 to 65 years of age with symptomatic and histologically active EoE.
Lytgobi Gets Accelerated Approval for Intrahepatic Cholangiocarcinoma
The approval was based on data from the open-label, single-arm phase 2b TAS-120-101 trial.
Glepaglutide Reduces Need for Parenteral Support in Short Bowel Syndrome Trial
Positive topline results were announced from a phase 3 trial evaluating glepaglutide in patients with short bowel syndrome.
Clinical Challenge: Chest Pain, Shortness of Breath, and Nausea
A woman in her mid-40s presents to the emergency department with a history of nausea and pleuritic-like chest pain. Can you make the diagnosis?
FDA Approves Aponvie for the Prevention of Postoperative Nausea, Vomiting
Aponvie is a proprietary IV injectable emulsion formulation designed to directly deliver aprepitant as a 30-second IV injection.
Unusual Cause of Chest, Abdominal Pain in Teen Following ACL Repair
A 17-year-old Black adolescent presents with a 1-day history of acute-onset abdominal pain, palpitations, and anemia. Can you make the diagnosis?
Case Study: Generalized Epigastric Pain and Syncope
A woman in her mid-50s presents to the emergency department with a history of nonradiating epigastric pain that began 36 hours ago. The patient notes that the pain has become more generalized. Can you make the diagnosis?
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