The FDA noted that it could not approve the BLA due to concerns regarding “the impact of patch-site adhesion on efficacy and indicated the need for patch modifications, and subsequently a new human factor study.”
After peanut SLIT, peanut skin test wheal, peanut-specific immunoglobulin E, and basophil activation decreased significantly, while peanut-specific immunoglobulin G4 increased significantly.
This study suggests that misunderstanding food label warnings could be dangerous for those with food allergies.
During the holidays, the very variety and complexity of foods served can make it difficult for someone with a food allergy to know what to avoid and what to try. And if someone does fall ill after eating holiday fare, pinpointing the culprit can take some real detective work.
