Neurodegenerative Disease and COVID-19: Assessing Outcomes in Hospitalized Patients
A team of researchers assessed COVID-19 outcomes in patients with neurodegenerative diseases compared with patients without such disease.
Dementia
Hyperuricemia, Gout Do Not Raise Dementia Risk
Hyperuricemia and gout may be associated with a lower risk for Alzheimer disease.
Tau Positron Emission Tomography Better Predicts Cognitive Decline Among Patients With Alzheimer Disease
The researchers sought to understand the prognostic value of tau positron emission tomography for predicting cognitive decline across the clinical spectrum of Alzheimer disease.
Clues to Memory Impairment in Cerebral Amyloid Angiopathy
The researchers’ objective was to assess the neuroimaging features of patients with cerebral amyloid angiopathy, or CAA, with and without objective memory impairment using tau PET imaging.
Sleep-Deprived Adults at Higher Risk for Dementia
While sleep dysregulation is a feature of dementia, it remains unclear whether the duration of sleep prior to old age is associated with dementia. The researchers examined the association between sleep duration and incidence of dementia using a 25-year follow-up.
Novel, Rare Variants Associated With Alzheimer Disease and Replicated in an Independent Cohort
The study researchers used deep whole-genome sequencing (WGS) to search for novel AD variants in 2247 individuals from 605 multiplex AD families from the National Institute on Mental Health and the National Institute on Aging (NIA) Alzheimer’s Disease Sequencing Project `data sets.
Researchers Propose New Definition of Brain Health
In correspondence published in The Lancet Neurology, researchers proposed a new definition of adult brain health.
Prostate Cancer Hormone Therapy Tied to Dementia, Depression in Younger Men
Findings from a recent study emphasize the importance of neurocognitive assessment in men undergoing ADT, especially in younger patients, according to investigators.
Pain Is a Prodromal Symptom, Correlate Rather Than Direct Cause of Dementia
In patients with dementia, pain is a correlate or prodromal symptom rather than a direct cause of dementia.
Lifestyle Changes May Aid Cognitive Abilities
Improvements in lifestyle risk factors for dementia can lead to short-term improvements in cognition among community-dwelling adults experiencing cognitive decline.
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