In 2013, a mother arrived at a Texas clinic with her 4-year-old son in tow. Three weeks earlier, he had been diagnosed with ringworm and given an antifungal (griseofulvin), but he had recently stopped eating. Concerned about his loss of appetite, she patiently waited for a doctor to see her son. When the doctor finally saw them, she informed him that it had been 2 days since her son ate. He also had begun to develop a rash on his face, trunk, and extremities and had some nasal congestion and an occasional cough. The doctor conducted a physical exam on the boy but there was nothing extraordinary other than his presenting symptoms: a sand paper–like erythematous rash and reddish mucosal tissue in his mouth and throat. He wasnt feverish, his cough was not persistent, and a rapid strep test was negative. Believing he had contracted a virus, the doctor sent him home to rest.