Scientists Issue Call to Become “Antiracist” in Cancer Care and Research
Even with an “exponential growth” of URM students, “faculty diversity would remain static well into the next 50 years.”
Clinical Trials
How Patients Lose Their Own Voices: Disparities in Patient-Reported Outcome Capture in Clinical Trials
It remains important to interrogate how structural discrimination influences the collection of patient-reported outcomes.
Lung Cancer Trials Supported by the Pharmaceutical Industry More Likely to Report Strong Evidence, Be Open Access
A study of clinical trials found no evidence of bias in the reporting of clinical trials supported by pharmaceutical companies compared with studies that had other funding sources.
African-American Participation Inadequate in Cancer Drug Trials
African-Americans are underrepresented in clinical trials leading to approval of cancer medications.
Eligibility Criteria a Significant Barrier to Patient Enrollment in Oncology Clinical Trials
Review of responses to clinical trial prompts within an oncology clinical pathways system identified barriers to increasing patient enrollment in clinical trials.
Antidepressant Trials Often Exclude Patients Displaying Suicidality, Study Finds
Of all the antidepressant efficacy trials conducted between 1991 and 2013, just 1 explicitly included patients who presented with suicidality.
Compliance With FDA Reporting Guidelines for Clinical Trials Is Low, Not Improving
Cohort study data from 2018 to 2019 suggest poor compliance with the US Food and Drug Administration reporting requirements for clinical trial sponsors.
Magnitude of Therapeutic Effects Crucial in FDA Approval of Non-RCT Treatments
The magnitude of therapeutic effects plays an important role in US Food and Drug Administration (FDA) approval of treatments based on nonrandomized clinical trials (RCTs), according to a study published in JAMA Network Open. RCTs are widely used to evaluate the safety and efficacy of new clinical interventions and medical devices. However, RCTs are often…
Understanding Therapeutic Misconceptions Associated With Clinical Trial Enrollment
Therapeutic misconception is an important type of false belief in medical research and medical practice.
Data Age in Clinical Trials Is About 3 Years at Publication
The median data age in clinical trials in journals with a high impact factor is about 3 years at publication.
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