Cancer

Predict Progression of Barrett's Esophagus to Esophageal Adenocarcinoma

Biomarkers May Help Predict Progression of Barrett’s Esophagus to Esophageal Adenocarcinoma

PHILADELPHIA — A series of microRNA expression signatures that may help to define progression of the precancerous condition Barrett’s esophagus into esophageal adenocarcinoma was reported recently in Cancer Prevention Research, a journal of the American Association for Cancer Research.

“Once a rare cancer representing only 5 percent of all esophageal cancers in the United States, esophageal adenocarcinoma is the cancer with the fastest-rising incidence — six-fold increase in the past three decades — and currently comprises more than 80 percent of all new esophageal cancer cases in this country,” said Xifeng Wu, M.D., chair of the Department of Epidemiology, Division of Cancer Prevention and Population Sciences at The University of Texas MD Anderson Cancer Center, in Houston. “To reduce the mortality of esophageal adenocarcinoma, the best hope in the near term is to detect it at its early stage, or even better, to prevent the progression of esophageal adenocarcinoma from its premalignant lesion, which is called Barrett’s esophagus.”

Cancer Screening Dogs

Cancer Screening Is for the Dogs

Early detection is paramount in the successful treatment of cancer. Colonoscopies and Pap smears have long been known to considerably lower mortality rates. However, improved screening methods are always needed. For example, lung cancer has a survival rate of about 15% because it is too often detected in the latter stages, which limits treatment options. Currently, imaging and sampling of blood, fluid, and tissue are the staples of diagnosis, but the future may also include a furrier option.

Dr. Michael Rosin

Michael Rosin

Here is the story of a doctor who lost his moral compass.

Dr. Michael A. Rosin was a well-respected community member, family man, and dermatologist in Sarasota, Florida. He specialized in Mohs micrographic surgery, which is a technique that excises skin cancer via removal of multiple thin layers of skin.

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