Investigators with Brigham and Women’s Hospital sourced data for this study from the Medicaid Analytic eXtract (MAX) and IBM Health MarketScan Research Database.
Researchers examined the effect of neuropeptides orexin-A, ghrelin, and neuropeptide Y on hypersomnia and hyperphagia. Both symptoms are more common in people with bipolar disorder.
In this study, patients were stratified by condition and suicide history and randomized to receive 600 mg/d extended-release lithium carbonate or placebo in addition to usual care.
