Opioids

Abuse-Deterrent Opioid Formulations: Barriers to Broader Use

Abuse-Deterrent Opioid Formulations: Barriers to Broader Use

By

Abuse-deterrent opioid formulations have not yet been widely accepted despite their proposed value in reducing opioid abuse and related mortality. Many of the current barriers to broader use are related to their higher cost compared with conventional formulations.

Integrating Treatments for Opioid Use Disorder and Infectious Diseases

Integrating Treatments for Opioid Use Disorder and Infectious Diseases

All healthcare providers have a role in combating the opioid use disorder epidemic and its infectious disease consequences.

Debunking Myths Around Treatment for Opioid Use Disorder

Debunking Myths Around Treatment for Opioid Use Disorder

By

Primary care office-based addiction treatment of opioid use disorder with buprenorphine is a realistic and scalable solution to address the overdose crisis in the United States.

Opioid Users More Likely to Have Complex Health Issues and Dealings With Criminal Justice System

Opioid Users More Likely to Have Complex Health Issues and Dealings With Criminal Justice System

By

Individuals taking opioids were found to be more likely to report physical and mental health issues and to have more frequent dealings with the criminal justice system compared with individuals not taking opioids.

FDA Takes Steps to Reconcile Needs of Patients With Chronic Pain, Efforts to Curb Opioid Epidemic

FDA Takes Steps to Reconcile Needs of Patients With Chronic Pain, Efforts to Curb Opioid Epidemic

By

A panel discussion event held at the US Food and Drug Administration gathered patients with chronic pain and FDA officials, to reconcile concerns around prescriptions of opioid medications with the needs of these patient populations.

Insurance Company Sets Goal of Reducing Opioid Overdoses by 25%

Insurance Company Sets Goal of Reducing Opioid Overdoses by 25%

By

Through their predictive analytics, Cigna can identify customers most likely to suffer from an overdose and can prompt interventions.

NIH Initiative Aims to Address Opioid Misuse Over Long Term

NIH Initiative Aims to Address Opioid Misuse Over Long Term

The HEAL initiative is being developed to help end opioid addiction over the long term.

Wearable Device Cleared for Use During Opioid Detoxification

Wearable Device Cleared for Use During Opioid Detoxification

By

Electrical pulses are sent through small needles that are inserted in the ear to combat the early stages of detoxification, leading to stabilization.

Public Support Only Moderate for Opioid Harm Reduction Strategies

Public Support Only Moderate for Opioid Harm Reduction Strategies

High levels of stigmatizing attitudes were reported toward people who use opioids.

NDA for First-of-Its-Kind Opioid Analgesic Submitted to FDA

NDA for First-of-Its-Kind Opioid Analgesic Submitted to FDA

By

NKTR-181 is a long-acting selective full mu-opioid agonist.

Opioid-Related Payments Linked to Increase in Opioid Rx

Opioid-Related Payments Linked to Increase in Opioid Rx

Findings suggest that opioid manufacturers should stop marketing to physicians in an effort to reduce opioid prescription rates.

Walmart Plans on Restricting Supply on Acute Opioid Prescription Fills

Walmart Plans on Restricting Supply on Acute Opioid Prescription Fills

By

For states that currently limit new acute opioid prescription fills to <7 days, Walmart and Sam's Club pharmacies will follow that state law.

First Opioid Lawsuit Targeting Pharmacy Benefit Managers

First Opioid Lawsuit Targeting Pharmacy Benefit Managers

A south Texas county included the 3 largest pharmacy benefit managers in a nationwide lawsuit focused on the opioid epidemic

Pharmacists Have Responsibility to Check Legitimacy of Opioid Rx

Pharmacists Have Responsibility to Check Legitimacy of Opioid Rx

Pharmacists should be aware that they are expected to take steps to make sure opioid prescriptions are written for legitimate medical purposes, and should document these efforts.

FDA: Social Media Companies Aren't Doing Enough to Stop Illegal Opioid Sales

FDA: Social Media Companies Aren't Doing Enough to Stop Illegal Opioid Sales

By

A recent report from the U.S. Senate Permanent Subcommittee on Investigations detailed how subcommittee members found it 'easy' to find fentanyl, pay for it and have it shipped to anywhere in the U.S.

Surgeon General Issues Advisory on Importance of Naloxone

Surgeon General Issues Advisory on Importance of Naloxone

By

In a statement, Surgeon General Jerome M. Adams, MD, MPH, said, "It is time to make sure more people have access to this lifesaving medication, because 77 percent of opioid overdose deaths occur outside of a medical setting and more than half occur at home."

Increasing Number of Benzodiazepine Prescriptions a Growing Threat in US

Increasing Number of Benzodiazepine Prescriptions a Growing Threat in US

By

Much like opioids, benzodiazepines can be highly addictive over a short period of time and can result in the use of analogue drugs.

FDA: Kratom Analysis Identifies Structural Similarities to Opioid Analgesics

FDA: Kratom Analysis Identifies Structural Similarities to Opioid Analgesics

By

To date, 44 deaths have been associated with the use of kratom.

Prescription Opioid Use Linked to Increased Satisfaction for Some Patients

Prescription Opioid Use Linked to Increased Satisfaction for Some Patients

Researchers sought to assess whether prescription opioid use is associated with satisfaction with care.

More Opioid Prescriptions Seen in Those With Lower Socioeconomic Indicators

More Opioid Prescriptions Seen in Those With Lower Socioeconomic Indicators

County-level socioeconomic factors are associated with opioid prescriptions among disabled Medicare beneficiaries.

Slow-Release Oral Morphine May Be Valuable for the Treatment of Opioid Use Disorders

Slow-Release Oral Morphine May Be Valuable for the Treatment of Opioid Use Disorders

By

Data suggest that slow-release oral morphine may be a promising candidate for oral opioid agonist therapy.

Urine Drug Testing Policy Can Help Clinicians Make Decisions About Opioid Treatment

Urine Drug Testing Policy Can Help Clinicians Make Decisions About Opioid Treatment

By

Clinicians should use immunoassay screens and urine drug tests to determine compliance with chronic opioid therapy.

Behavior of Opioid Prescribing: Admitting What We Don't Know

Behavior of Opioid Prescribing: Admitting What We Don't Know

By

Opioid prescriptions should be tailored based on risk factors that correlate with future addiction rates and the pertinent outcome markers, but this information is still lacking.

FDA: Once-Monthly Injection Approved for Opioid Use Disorder

FDA: Once-Monthly Injection Approved for Opioid Use Disorder

Buprenorphine has been shown to reduce opioid withdrawal symptoms and the desire to use opioids.

State-Level Declarations of Opioid Emergency Raise Public Awareness of Addiction

State-Level Declarations of Opioid Emergency Raise Public Awareness of Addiction

By

With opioid-related mortality rates on the rise, most states have enacted specific policies aimed at reducing prescriptions for these medications.

FDA Permits Marketing of Device to Reduce Symptoms of Opioid Withdrawal

FDA Permits Marketing of Device to Reduce Symptoms of Opioid Withdrawal

By

The FDA has approved a device designed to provide relief from opioid withdrawal symptoms when placed behind the ear.

Addiction Policy Expert From Obama Administration Addresses the Opioid Epidemic

Addiction Policy Expert From Obama Administration Addresses the Opioid Epidemic

By

Keith Humphreys, PhD, who served as senior policy advisor at the White House Office of National Drug Control Policy in the Obama Administration, shared his views on the opioid epidemic.

Do Prescription Drug Monitoring Programs Influence Opioid Prescribing?

Do Prescription Drug Monitoring Programs Influence Opioid Prescribing?

By

Although registration in prescription drug monitoring programs was shown to lead to statewide declines in high-risk opioid prescriptions, these declines were similar to those observed in non-PDMP registrants.

Fentanyl Detected in Over Half of Drug Overdose Deaths in 2016

Fentanyl Detected in Over Half of Drug Overdose Deaths in 2016

Carfentanil, furanylfentanyl, and acetylfentanyl were the fentanyl analogs identified most frequently, and fentanyl analogs were present in more than 10% of opioid overdose deaths in 4 states.

Effects of Medicare Opioid Formulary Coverage Restrictions for 2006 to 2015

Effects of Medicare Opioid Formulary Coverage Restrictions for 2006 to 2015

Medicare Part D formularies increasingly used quantity limits and prior authorization to restrict daily allowable prescribed dosing of opioids.

Free E-Newsletter