Pediatrics

Adolescents With Autism Spectrum Disorder May Benefit From a Dance Intervention

Researchers studied whether a dance intervention may be beneficial for adolescents with autism spectrum disorder.

Orkambi Indication Expanded to Include More Children With Cystic Fibrosis

The safety profile of Orkambi was found to be similar in patients aged 1 to less than 2 years compared with those 2 years of age and older.

Sensorineural Hearing Loss Risk in Children Tied to Oral Macrolide Therapy

Researchers sought to evaluate the risk for hearing loss with outpatient use of oral macrolide therapy in children, adolescents, and young adults.

Lomecel-B Granted Fast Track Status for Hypoplastic Left Heart Syndrome

Lomecel-B is delivered via intramyocardial injection.

Amoxicillin Remains Most Effective First-Line Treatment for Acute Otitis Media

Researchers compared the effects of amoxicillin with other broad-spectrum antibiotics on the risk for treatment failure and reinfection in children with uncomplicated acute otitis media.

Behavioral Therapy Tied to Reduced Tic Severity in Youth With Tourette Syndrome

Researchers sought to determine the long-term durability of CBIT in youth with Tourette syndrome and persistent motor or vocal tic disorders.

Pediatric Kidney Transplant Rate Lower at For-Profit Dialysis Facilities

Dialysis facility profit status was associated with longer time to waitlisting and kidney transplantation, investigators reported.

Back to School: Time For COVID-19 Vaccinations

Most parents of young children eligible for COVID-19 vaccines said they are reluctant to get them vaccinated, including 43% who say they will “definitely not” do so.

Diet-Induced Remission in Pediatric Crohn Disease Linked to Metabolome Changes

Researchers examined changes in fecal metabolites resulting from either the Crohn disease exclusion diet plus enteral nutrition or the exclusive enteral nutrition diet and the association with remission.

Stelara Approved for Pediatric Psoriatic Arthritis

The approval is supported by evidence from adequate and well-controlled studies of Stelara.

The Gut-Brain Connection: Understanding GI Symptoms in Autism Spectrum Disorders

Deborah Goldman, MD, and Kara Gross Margolis, MD, discuss the importance of understanding gastrointestinal symptoms in children with autism to drive better care.

Ztalmy Oral Suspension Now Available for CDKL5 Deficiency Disorder

The approval was based on data from the phase 3 Marigold study that included patients aged 2 to 19 years with genetically confirmed CDKL5 gene mutation.

Spotlight on Pediatric Bipolar Disorder

The main focus of the debate surrounding pediatric bipolar disorder pertains to the concept of a prepubertal subtype of the disorder.

Children With Autism More Likely to Have Obstructive Sleep Apnea Symptoms

Researchers sought to assess OSA symptoms and age of OSA diagnosis in children with and without ASD.

Autism Among Top Factors for Likelihood of Bullying Exposure in Children

Researchers sought to investigate the factors that may modify the association between neurodevelopmental disorders and the risk for being bullied.

Case Study: Increasing Frequency of Nosebleeds Leads to Graves Disease Diagnosis

A 14-year-old adolescent with epilepsy presents with increasing episodes of nosebleeds, increased rate of speech, leg pain with little exercise, and irritable mood. Learn how delayed diagnosis of Graves disease affected her treatment.

Pneumococcal 15-Valent Conjugate Vaccine Approved for Pediatric Use

For children, Vaxneuvance is administered as a 4-dose series at 2, 4, 6 and 12 through 15 months of age (and at least 2 months after the 3rd dose).

Flucelvax Quadrivalent Approval Expanded to Include Younger Patients

The expanded approval was based on data from a phase 3 study that compared Flucelvax Quadrivalent to a US-licensed comparator quadrivalent influenza vaccine.

Lower Ventral Striatum Activity Associated With Depression in Teens

Researchers used data from a European sample of teens from the IMAGEN Consortium study, which measured resting-state fMRI activity at age 14, 16, and 18.

Motor and Language Deficits Common in Children Evaluated for Autism

In a cross-sectional study, researchers explored the co-occurrence for motor and language impairments in children evaluated for autism.