Pediatrics

Mode of Delivery May Be a Risk Factor for Early Childhood Atopic Dermatitis

A cohort study of mother and child pairs investigates the association between mode of delivery and atopic dermatitis in children 5 years of age and younger.

Early Childhood Sleep Problems May Contribute to Risk for Probable ADHD Diagnosis

Investigators sought to evaluate the association between early childhood sleep and probable childhood ADHD diagnosis and if these prospective associations are mediated by childhood circulating inflammatory markers.

Odactra Approved for Adolescents With House Dust Mite Allergic Rhinitis

Odactra is an allergen extract indicated as immunotherapy for the treatment of HDM-induced allergic rhinitis.

Rotavirus Increases Risk for Neurologic Disease, Poor Outcomes in Pediatric Patients

Researchers evaluated whether there is an association between rotavirus infection and extraintestinal complications in pediatric patients.

Gluten-Free Diet Decreases Functional GI Disorders in Pediatric Celiac Disease

Researchers assessed the prevalence of functional gastrointestinal disorders in children with celiac disease who follow a gluten-free diet.

Adacel Approved for Use During Pregnancy to Prevent Pertussis in Infants

The approval was based on a re-analysis of data from on observational study of Tdap vaccine effectiveness in the US.

Few Parents Introduce Infants to Top Food Allergens by 7 Months of Age

A survey developed by pediatricians and allergists identified current practices regarding the introduction of food allergens to children aged 7 months to 3.5 years.

Wegovy Gains Approval for Treating Obesity in Adolescents

Wegovy contains semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist.

Interventions Targeting Repetitive Negative Thinking May Improve Depression, Anxiety

Can reducing RNT with psychological treatment approaches help improve youth depression and anxiety?

Gaming and Online Gambling in Adolescence Increases Risk for Problem Gambling

In a review of 45 studies, investigators looked at whether activities with gambling-like features in adolescence and young adulthood can contribute to gambling problems.

Parental Vaccination Reduces Hospitalization Risk Due to COVID-19 in Children

Researchers sought to analyze COVID-19 vaccination status among parents of hospitalized children younger than age 5 years with COVID-19 infection during the Delta and Omicron waves.

Semaglutide Plus Lifestyle Intervention Beneficial in Adolescents With Obesity

Investigators sought to evaluate the effect of subcutaneous semaglutide therapy for treatment of obesity in adolescents.

Benzodiazepine Prenatal Exposure No Risk for Autism Spectrum Disorder and ADHD

Is prenatal benzodiazepine exposure associated with increased risks for autism spectrum disorder or attention-deficit/hyperactivity disorder?

Consistent Results Observed With Topical Roflumilast in Second Atopic Dermatitis Trial

The INTEGUMENT-2 trial included patients 6 years of age and older with mild to moderate atopic dermatitis involving at least 3% body surface area.

Empagliflozin Significantly Reduces HbA1c in Children With Type 2 Diabetes

The trial evaluated the efficacy and safety of empagliflozin and linagliptin in 175 patients 10 to less than 18 years of age with type 2 diabetes.

Pfizer, BioNTech Submit EUA Request for Bivalent COVID-19 Vaccine in Younger Children

The bivalent vaccine contains the original strain of the SARS-CoV-2 virus and a strain from the BA.4 and BA.5 lineages of the Omicron variant.

AAP Releases “Choosing Wisely” Recommendations for Pediatric Emergency Medicine

As part of the Choosing Wisely campaign, the American Academy of Pediatrics (AAP) has released a new list of 5 tests and procedures commonly ordered in pediatric emergency medicine that physicians and patients should question. Choosing Wisely is an American Board of Internal Medicine (ABIM) Foundation initiative that aims to promote discussions between clinicians and…

Evinacumab Under Review for Pediatric Homozygous Familial Hypercholesterolemia

Evinacumab is a fully-human monoclonal antibody that binds to and blocks the function of angiopoietin-like 3.

Amoxicillin Shortage Prompts Guidance on Pharmacy Compounding

The guidance provides steps to address the potential for cross-contamination.

Sezaby Approved to Treat Seizures in Term and Preterm Infants

The FDA has approved Sezaby (phenobarbital sodium powder for injection) for the treatment of neonatal seizures in term and preterm infants.