Oncology

Weighing the Efficacy and Toxicity of CAR T-Cell Therapy

Researchers sought to determine the balance between the efficacy and toxicity when administering CAR T-cell therapy.

Early Death May Be Common in Cancer Patients Taking Immune Checkpoint Inhibitors

Results of a real-world study suggest that early death may be common among cancer patients taking immune checkpoint inhibitors.

Brain Tumors Are Major Contributor to US Cancer Burden 

Data suggest that brain tumors are the fifth most prevalent cancer type in the US, after female breast cancer, prostate cancer, colorectal cancer, and melanoma.

Cancer Patients With Diabetes May Have Worse Outcomes on ICIs

Cancer patients with type 2 diabetes may have worse survival outcomes on immune checkpoint inhibitor therapy, a new study suggests.

Parenteral Opioids Effective, Safe for Relieving Dyspnea at End of Life

Researchers explored the effectiveness and safety of parenteral morphine, oxycodone, and hydromorphone in treating terminal dyspnea in patients with cancer.

Cancer Patients Report Better Experiences With Telemedicine Than With In-Person Care

Cancer patients who use telemedicine report better experiences than cancer patients treated in person, according to a new study.

Ultrasound Technique Delivers Paclitaxel Across Blood-Brain Barrier in Glioblastoma

An ultrasound technique allows for delivery of albumin-bound paclitaxel across the blood-brain barrier in patients with recurrent glioblastoma, a study suggests.

Sex Hormones Linked to Risk of Gastrointestinal Cancers

Higher levels of certain sex hormones are associated with an increased risk of some gastrointestinal cancers, a meta-analysis suggests.

Extreme Poverty Associated With Increased Risk of Pediatric ALL Relapse

Researchers sought to determine the impact of extreme poverty on the risk of relapse in pediatric patients with ALL.

Body Roundness May Increase Risk for Colorectal Cancer

Researchers investigated whether body roundness index is associated with a person’s risk of developing colorectal cancer.

Food Deserts, Swamps Linked to Increased Risk of Death From Obesity-Related Cancers

US counties with food deserts or food swamps tend to have higher rates of death from obesity-related cancers, a study suggests.

Disulfiram and Copper Plus Chemotherapy Not Effective for Glioblastoma

Researchers evaluated the efficacy and safety of disulfiram and copper as add-on alkylating chemotherapy in patients with recurrent glioblastoma.

Newly Identified Prostate Cancer Subtypes May Respond Differently to Treatment

Researchers say they have identified 4 subtypes of prostate cancer with distinct biological and clinical features, and these subtypes may respond differently to treatment.

Black Men With Metastatic Prostate Cancer More Frequently Refuse Chemotherapy

A recent study found a racial disparity in the use of guideline-concordant treatment for metastatic prostate cancer.

Peritumoral Lidocaine Injection Before Breast Cancer Surgery Improves Outcomes

Breast cancer patients who receive a peritumoral injection of lidocaine immediately before surgery have better survival outcomes, a study suggests.

Ibrutinib No Longer Approved for MCL, MZL: How This Change Will Affect Patients

The withdrawn approvals of ibrutinib for relapsed/refractory MCL and MZL are likely to have a limited impact on patients, experts say.

Older Men Continue to Be Overscreened for Prostate Cancer

Clinician-led discussion of PSA testing advantages was associated with overscreening among older men.

Pediatric Cancer Survivors Have 4-Fold Higher Risk of Death 40 Years After Diagnosis

From 15 to 40 years after diagnosis, pediatric cancer survivors have a roughly 4-fold higher risk of death than the general population, a study suggests.

Anal Cancer More Prevalent in IBD, Particularly Among Patients With Ulcerative Colitis

Researchers assessed the burden of anal human papillomavirus disease among patients with inflammatory bowel diseases.

Effectiveness of Acupuncture for Cancer-Related Sleep Disturbance

Researchers compared several traditional Chinese medicine modalities to determine which may benefit patients with cancer who experience sleep disturbance.