Neurology

FDA Approves Ingrezza for Huntington Disease Chorea

Nearly half of patients receiving Ingrezza saw a more than 40% reduction in Huntington disease chorea severity by the end of the treatment period.

Essential Oils Enhance Cognition in Healthy Older Adults During Sleep

In a small, randomized controlled trial, researchers assessed whether the use of essential oils at night improved cognition in healthy older adults.

Examining the Role of Viral Infections in the Pathophysiology of Multiple Sclerosis

Some viral infections have been implicating in either driving the pathophysiology of multiple sclerosis or making it worse.

Exercise Combined With Cognitive Training Helps Older Adults With MCI

Researchers sought to assess whether aerobic-resistance exercises with cognitive training and vitamin D improve cognition in older adults with mild cognitive impairment.

Depression Diagnosis Tied to Increased Dementia Risk

Researchers sought to examine associations of early-, middle-, and late-life depression with the risk of developing dementia.

Blood Tests for Detecting Alzheimer Disease Show Promise: Research From AAIC 2023

Blood tests for Alzheimer disease may improve diagnostic accuracy and treatment options.

Alzheimer Disease Prevalence Highest in East, Southeast US

Researchers sought to estimate the prevalence and number of adults living with Alzheimer disease across US states and counties.

Cognition in Older Adults Not Improved By Meditation and Language Training

In a randomized trial, researchers investigated the effects of 18 months of either meditation training or non-native language training on cognitive function in older adults who were cognitively healthy.

Brain Fitness Program May Benefit ADHD, Concussion, and Memory Loss

Researchers evaluated the benefits of a multimodal 12-week “brain fitness program” for individuals with ADHD, concussion, and memory loss.

Investigating Guillain-Barre Syndrome and Vaccines: Is There a Link?

Research on the potential link between vaccines and Guillain-Barre syndrome has mixed findings — some indicate a minimal association; others do not find a significant causal relationship.

Dementia Risk Assessment Models Have Limited Ability in Predicting Disease

In a prospective, population-based study, researchers investigated the clinical utility of multifactorial risk prediction models in estimating patients’ 10-year dementia risk.

How Does Coffee Consumption Affect Connectivity of the Brain’s Neural Networks?

Researchers assessed the neurobiological impact of coffee consumption on brain connectivity via resting-state functional magnetic resonance imaging.

Cognitive Biotype, New Depression Subtype, Resistant to Common Antidepressants

Researchers sought to assess how objective cognitive deficits in depression are associated with symptoms, neural circuits, and treatment outcomes.

Chlamydia pneumoniae May Be a Risk Factor for Multiple Sclerosis

In a meta-analysis, researchers evaluated the relationship between Chlamydia pneumoniae infection and the development of multiple sclerosis.

Incident Myocardial Infarction Tied to Faster Cognitive Decline Over Time

In an observational cohort study, researchers assessed whether incident MI is associated with changes in cognitive function after adjusting for pre-MI cognitive trajectories.

Earlier Age at Type 2 Diabetes Onset May Lead to Higher Dementia Risk

In a large population-based cohort study, researchers evaluated whether the association of prediabetes with dementia is explained by the intervening onset of diabetes.

Family History, Psychiatric Comorbidities Predict Tic Disorder Persistence Into Adulthood

Researchers sought to estimate the percentage of tic disorders in childhood that continued into adulthood, as well as the risk factors associated with tic disorder persistence.

Could Skeletal Muscle Adiposity Be a Risk Factor for Cognitive Decline?

In a longitudinal study, researchers assessed muscle adiposity and evaluated cognitive function in older adults.

Quality Slow-Wave NREM Sleep May Be Protective in Alzheimer Disease

In an observational study, researchers looked at factors, such as slow-wave NREM sleep, that could explain the differences in cognitive function among individuals with the same level of brain pathology.

Can Daily Internet Use Alleviate Dementia Risk in Older Adults?

Researchers sought to assess the long-term risk for dementia in older adults with regular internet usage and compare dementia risk in baseline internet usage to educational level, race/ethnicity, sex and generation, as well as the potential detrimental effects of excessive usage.