Cardiology

Apixaban Tied to Lower Risk of Gastrointestinal Bleeding

Findings were consistent for patients aged 80 years or older and patients with chronic kidney disease, who are often underrepresented in clinical trials.

Blood Culture-Negative Endocarditis: Individualized Diagnosis, Management

Primary care providers are the frontline in the prompt identification of potential blood culture-negative endocarditis cases.

Low-Dose Statin Bests Six Commonly Used Cholesterol Health Supplements

The study included adults aged 40 to 75 years with no history of cardiovascular disease, an LDL-C of 70-189 mg/dL, and a 5-20% 10-year risk of ASCVD.

Apixaban Bests Rivaroxaban in “Emulated” Trial of Patients With Afib and VHD

Apixaban and rivaroxaban are both factor Xa inhibitors.

Etripamil Nasal Spray Looks Promising for Self-Administered PSVT Treatment

Etripamil is a self-administered nasal spray designed to be a rapid-response therapy for episodic cardiovascular conditions.

Smartphone-Recorded Steps Affect Cardiovascular Risk Factors in Working-Age Adults

A study was conducted to determine the relationship between smartphone-recorded daily steps and changes in risk for cardiovascular disease.

OAC in Patients With AF and COVID-19 Lowers Rates of Death, Thrombotic Events 

Researchers assessed the relationship between oral anticoagulation for patients with COVID-19 and AF and incidence of in-hospital thrombotic events and death.

Early VT Ablation Does Not Associate With Reduced Mortality in Patients With an ICD

A study was conducted to determine the efficacy of treating patients with ICDs and ventricular tachycardia with early catheter ablation.

A Mysterious Case of Heart Palpitations in Young Woman

A 31-year-old woman with no significant medical history presents with intermittent heart palpitations, dizziness, shortness of breath, and fatigue provoked by exercise. Can you make the diagnosis?

ACC Recommendations on the Role of Nonstatin Therapies for Lowering LDL-C

In 2021, an expert panel assembled to review gaps in care related to treatments meant to lower LDL-C in patients with atherosclerotic cardiovascular disease.

Rate of Ruptured Cerebral AVMs Increased Since ARUBA Trial

A study was conducted to determine incidence of hospitalizations for cAVM rupture before and after the ARUBA trial.

SGLT-2 Inhibitors Show Benefit in Heart Failure With Preserved Ejection Fraction

Investigators conducted a meta-analysis of randomized controlled trials on the effect of SGLT-2 inhibitors on patients with HFpEF.

Dapagliflozin Beneficial Regardless of Ejection Fraction in Heart Failure

The findings were consistent across key subgroups examined (eg, LVEF<60%, diabetes)

Cardiovascular Effects of Pre-Workout Caffeine and Energy Supplements

Gregory M Marcus, MD, MAS, and Jeffrey J. Hsu, MD, PhD, discuss the effect of caffeine and energy supplements on risk for cardiovascular events.

A Quarter of Patients With Implantable Electronic Devices Have Subclinical AF

A study was conducted to determine the epidemiology of subclinical atrial fibrillation in patients with cardiac implantable electronic devices.

USPSTF Issues Final Recommendations on Statin Use for Primary Prevention of CVD

These recommendations apply only to individuals without a history of CVD and who are not already taking statins.

Spotlight on Increasing Myocardial Infarction Disparities in Young Women

Viola Vaccarino, MD, PhD, Yuan Lu, ScD, and Ersilia M. DeFilippis, MD, discuss increasing rates of myocardial infarction among young women.

Pfizer Ends Development of Drug for LMNA-Related Dilated Cardiomyopathy

PF-07265803 is an investigational selective, oral, small-molecule inhibitor of the p38a mitogen activated protein kinase pathway.

Sotagliflozin Under Review for Heart Failure Treatment

Sotagliflozin is an investigational dual sodium-glucose co-transporter types 1 and 2 (SGLT1, SGLT2) inhibitor.

Omega-3 Fatty Acid Supplementation Effective for Lowering Blood Pressure

A study was conducted to determine a more precise dose-response effect for omega-3 fatty acids on blood pressure in the general population.