HealthDay News — Higher levels of caffeinated beverage intake may be a trigger for migraine headache on that day among adults with episodic migraines, according to a study published in the American Journal of Medicine.

Elizabeth Mostofsky, ScD, from Beth Israel Deaconess Medical Center in Boston, Massachusetts, and colleagues evaluated the role of caffeinated beverage intake as a potential trigger for migraine headache using data from 98 participants (mean age, 35.1 years) with episodic migraine who completed ≥6 weeks of diaries between March 2016 and October 2017.

The participants reported 825 migraines over 4467 days of observation. The researchers observed a significant, nonlinear association between the number of caffeinated beverages and the odds of migraine headache occurrence on that day. There was variance in the associations by habitual intake and oral contraceptive use. Minimal consumption (1 or 2 servings of caffeinated beverages) was not associated with headaches on that day; however, 3 servings may be associated with higher odds of headache, even after adjusting for daily alcohol intake, stress, sleep, activity, and menstrual bleeding. A similar pattern was seen for associations between caffeinated beverages and headaches on the following day.

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“Additional research is needed to examine the potential effect of caffeine on symptom onset in the subsequent hours and the interplay of sleep, caffeine, anxiety, environmental factors, and migraine,” the authors write.

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