The Centers for Disease Control and Prevention’s (CDC) Advisory Committee on Immunization Practices (ACIP) has released the recommended child and adolescent immunization schedule for ages 18 years or younger in the United States for 2022.

The immunization schedule has been approved by CDC, the American Academy of Pediatrics, the American Academy of Family Physicians, the American College of Obstetricians and Gynecologists, the American College of Nurse-Midwives, the American Academy of Physician Associates, and the National Association of Pediatric Nurse Practitioners.

Major changes to the child and adolescent immunization schedule for 2022 include the following:


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Dengue Vaccination

  • New section added for routine dengue (Dengvaxia) vaccination in areas with endemic dengue. 
  • 9 to 16 years of age living in dengue endemic areas and laboratory confirmation of previous dengue infection: 3-dose series administered at 0, 6, and 12 months. 
  • Endemic areas include Puerto Rico, American Samoa, US Virgin Islands, Federated States of Micronesia, Republic of Marshall Islands, and the Republic of Palau.

Haemophilus influenzae type b (Hib) Vaccination

  • Note was revised to include recommendations for using Vaxelis for routine and catch-up vaccination.
  • Routine vaccination for ActHIB, Hiberix, Pentacel, or Vaxelis: 4-dose series (3 dose primary series at age 2, 4, and 6 months, followed by a booster dose* at age 12 to 15 months)
    • *Vaxelis is not recommended for use as a booster dose. A different Hib-containing vaccine should be used for the booster dose.
  • The catch-up schedule for Vaxelis can be found here.

Hepatitis A Vaccination

  • Note was revised to clarify the recommended age for routine vaccination.
    • 2-dose series (minimum interval: 6 months) at age 12 to 23 months.

Hepatitis B Vaccination

  • Note was revised to clarify the recommendation for post-vaccination serologic testing and revaccination.
  • Post-vaccination serology testing and revaccination (if anti-HBs <10mIU/mL) is recommended for certain populations, including:
    • Infants born to HBsAg-positive mothers
    • Hemodialysis patients
    • Other immunocompromised persons

Human Papillomavirus Vaccination

  • Note was revised to clarify the number of doses for persons with immunocompromising conditions.
  • Immunocompromising conditions, including HIV infection: 3-dose series, even for those who initiate vaccination at age 9 through 14 years.

Measles, Mumps, and Rubella (MMR) Vaccination

  • Note was updated to include information on recommendations for use of measles, mumps, rubella, varicella (MMRV) vaccines.
  • For routine vaccination, MMR or MMRV may be administered.
    • For dose 1 in children age 12 to 47 months, it is recommended to administer MMR and varicella vaccines separately. MMRV may be used if parents or caregivers express a preference.
  • For catch-up vaccination, the maximum age for use of MMRV is 12 years.
    • The minimum interval between MMRV doses is 3 months.

Meningococcal ACWY Vaccination

  • Note was updated to state:
    • Meningococcal ACWY vaccines may be administered simultaneously with Meningococcal B vaccines if indicated, but at a different anatomic site, when feasible.

Varicella Vaccination

  • Note was updated to include information on recommendations for use of MMRV.
  • For routine vaccination, varicella vaccine or MMRV may be administered.
    • For dose 1 in children age 12 to 47 months, it is recommended to administer MMR and varicella vaccines separately. MMRV may be used if parents and caregivers express a preference.
  • For catch-up vaccination, the maximum age for use of MMRV is 12 years.

For additional guidance on the use of each vaccine appearing in the schedule, including precautions and contraindications, clinicians can view the respective ACIP vaccine recommendations at cdc.gov. In addition, vaccine catch-up guidance can be found here.

Interim clinical considerations for the use of COVID-19 vaccines can be found here.

Reference

US Centers for Disease Control and Prevention. Wodi AP, Murthy N, Bernstein H, et al. Advisory Committee on Immunization Practices Recommended Immunization Schedule for Children and Adolescents Aged 18 Years or Younger — United States, 2022. MMWR Morb Mortal Wkly Rep 2022;71:234–237. https://www.cdc.gov/mmwr/volumes/71/wr/mm7107a2.htm.

This article originally appeared on MPR