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Wuling Capsule for Insomnia in Adults: How Safe and Effective Is It?

In a retrospective, systematic review, researchers assessed the effectiveness and safety profile of Wuling for the treatment of insomnia.

Pembrolizumab a Successful Adjuvant Treatment for High-Risk Melanoma

Recurrence-free survival in patients with melanoma treated with pembrolizumab are reported.

Malnutrition Linked to Increased Mortality, Infection Risk in Alcoholic Hepatitis

A team of researchers sought to determine the effects of malnutrition on the risk for infection in patients hospitalized with alcoholic hepatitis.

The Gut Microbiome and ICS Response to Wheezing in Pediatric Asthma

Among children with asthma, are inhaled corticosteroids effective in controlling wheezing that is associated with these children’s gut microbiome?

Novel Immunotherapy Combos Show Promise in Stage III Non-Small Cell Lung Cancer

Combining either oleclumab or monalizumab with durvalumab provided a progression-free survival benefit over durvalumab alone.

Maintenance of Intermittent Fasting for Weight Loss and Metabolic Health Improvements

A team of investigators evaluated the success of a time-restricted eating intervention among individuals at increased risk of developing type 2 diabetes.

Psoriasis Linked With Risk for Severe and Rare Infections

The risk for severe and rare infections in patients with psoriasis—mild or severe—is assessed.

Impact of Physical Activity on Risk for Disabling Dementia by Gender

In a large, prospective cohort study, researchers assessed the association between daily total physical activity and the risk of developing disabling dementia in the general Japanese population.

Efficacy Response Maintained With Deucravacitinib in Plaque Psoriasis Trial

The POETYK PSO-LTE trial evaluated deucravacitinib 6mg orally once daily in 1221 adults with moderate to severe plaque psoriasis.

Healthy Lifestyle Decreases Risk for Peripheral Artery Disease

A prospective cohort study was conducted to determine the relationship between multiple modifiable lifestyle factors and risk for peripheral artery disease.

Cumulative Lifetime Excess Weight Associated With Colorectal Cancer Risk

Researchers sought to determine whether cumulative lifetime excess weight was associated with risk for colon cancer.

Adjuvanted Enterovirus 71 Vaccine Is Highly Effective in Infants and Children

Researchers assessed the efficacy of an adjuvanted enterovirus 71 (EV71) vaccine for the prevention of EV71-associated infections among infants and children.

Cognitive Impairment 3 to 12 Months After COVID-19 Hospitalization

Researchers assessed the frequency and severity of cognitive impairments over time and specifically 1 year after hospitalization in patients who contracted COVID-19.

Trial Evaluating Tiragolumab Combo in PD-L1 High NSCLC Misses PFS Endpoint

The phase 3 study compared tiragolumab plus atezolizumab with placebo plus atezolizumab in adults with PD-L1 high locally advanced, unresectable or metastatic NSCLC.

ACC Statement on Respect, Civility, and Inclusion in the Cardiovascular Workplace

The American College of Cardiology has issued a policy statement regarding civility, inclusion, and respect in the cardiovascular workplace.

Can Childhood Trauma Increase the Risk for Multiple Sclerosis in Women?

In a prospective cohort study, researchers assessed whether adverse childhood experiences may increase the risk for multiple sclerosis in women.

New Model Improves Life Expectancy Estimates in Prostate Cancer Population

A novel life expectancy calculator could allow for more personalized management of men with prostate cancer.

Integrated Cognitive and Balance Intervention Improves Depression Symptoms

The ENGAGE-2 Mechanistic Pilot trial was a randomized clinical trial conducted at the University of Illinois at Chicago and Stanford University between 2019 and 2020.

Link Between Arthritis Drugs and Alzheimer Disease Risk

Researchers sought to evaluate whether there is any evidence from real-world data on treatment with tofacitinib, tocilizumab, or tumor necrosis factor and the risk for ADRD.

Cannabis Flower and Concentrates Most Effective for Quick Nausea Relief

Researchers examined the effectiveness of various cannabis products for relieving nausea in patients.