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Prostate Cancer Family History Warrants Earlier Risk-Based Screening

A man’s optimal screening age depends on the number of first-degree male relatives affected by prostate cancer and their age at onset, investigators suggest.

Attention-Deficit Hyperactivity Disorder Symptoms and Secondhand Smoke Exposure Among Children

There have not been very many studies which examined the association between secondhand smoke and ADHD symptoms in children. Thus, the researchers sought to evaluate whether or not there is a relationship between the two.

Prognostic Understanding Influences Patients’ Lung Cancer Care Decisions at the End of Life

Researchers assessed the associations between patients’ understanding of their prognosis and their end-of-life care decisions.

FDA to Review Dry Powder Inhalation Formulation of Tyvaso

Tyvaso DPI is an investigational drug-device combination therapy consisting of a dry powder formulation of treprostinil.

Ayvakit Approved for Advanced Systemic Mastocytosis

The approval was based on data from 2 multicenter, single-arm, open-label clinical trials that evaluated Ayvakit in 53 patients with advanced systemic mastocytosis.

FDA: Systemic Side Effects Reported After Hand Sanitizer Application

The Agency reviewed case reports from the FAERS database and calls from US poison control centers related to systemic symptoms after applying alcohol-based hand sanitizers to the skin.

A Screening Program for Unhealthy Alcohol Use Integrated Into Electronic Health Record Software Feasible and Effective

This study asks: How are commonly used screening methods for alcohol and drug use associated with implementation outcomes among adult patients in primary care clinics, and what is the best approach for implementing electronic health record–integrated screening?

Post-Traumatic Coma Prognosis is Difficult to Predict

Bianciardi and colleagues investigated the patterns of microbleeds associated with post-traumatic coma and the recovery of consciousness in young comatose patients.

Potential Association Between Celiac Disease and Autism Spectrum Disorder

Investigators attempted to analyze the link between celiac disease and autism spectrum disorder based on previously published research.

Age and Stage at Breast Cancer Diagnosis Don’t Account for Racial Disparities in Distant Metastases

Black patients were more likely than White patients to have distant metastases.

Preoperative LAMA/LABA Reduces Surgical Complications in Lung Cancer With COPD

Preoperative use of a LAMA with a LABA was associated with significant improvements in lung function compared with use of LAMA alone in patients with lung cancer and COPD.

NVX-CoV2373 Nanoparticle Vaccine Effective Against COVID-19 B.1.351 Variant

A phase 2a-b study was conducted in South Africa to assess the safety and efficacy of the NVX-CoV2373 vaccine.

Prenatal, Postnatal Antibiotic Exposure and Atopic Dermatitis in Children

A link between pre- and postnatal exposure to antibiotics and the risk for atopic dermatitis is investigated.

Mindfulness Programs Appear to Improve Emotional Distress Symptoms Among Patients With Rheumatic Disease

Researchers compared the effectiveness of full-length vs brief mindfulness training programs for improving anxiety among patients with rheumatic disease.

Non-Food Prebiotic, Probiotic, and Synbiotic Use has Increased Among the United States Population

Investigators aimed to describe non-food prebiotic, probiotic, and synbiotic use by US adults and children and reported reasons for using these products.

New-Onset SVT Following Colonoscopy Bowel Prep Explored in Case Series

A significant percentage of affected patients were observed to have dilated atria and left ventricular hypertrophy.

Call for Global Adoption, Enforcement of Evidence-Based Tobacco Control Policies

Although considerable progress has been observed in countries around the world in reducing the prevalence of smoking tobacco use, a large implementation gap remains with respect to tobacco control.

AHA/ASA 2021 Guidelines for Secondary Stroke Prevention

Here are highlights from the American Heart Association and American Stroke Association’s 2021 evidence-based guidelines for preventing another stroke after a first stroke or transient ischemic attack.

Epclusa Approved for Younger Patients With Chronic Hepatitis C

The expanded approval was based on data from an open-label phase 2 trial that evaluated Epclusa in 41 patients 3 years to less than 6 years of age with chronic HCV infection.

Metformin May Slow Emphysema Progression, Systemic Consequences

Metformin has demonstrated potential for slowing emphysema progression and its systemic consequences.