The phase 3 COSMOS study evaluated the efficacy and safety of guselkumab in 285 adults with active PsA who had an inadequate response to anti-tumor necrosis factors.
The approval was based on data from the open-label, randomized phase 3 Inter-B-NHL Ritux 2010 trial.
Investigators assessed whether the increase in early-onset colorectal cancer incidence is a product of increased colonoscopy screening or due to other factors.
The safety and feasibility of treating patients with infantile hemangiomas with a combination of pulsed-dye laser (PDL) and 0.5% timolol maleate solution is investigated.
The application is supported by data from the phase 2 BEYOND study.
Regulora is designed to provide seven 30-minute sessions of remote behavioral therapy based on gut-directed hypnotherapy.
Age, lymphovascular invasion, and histology predicted pathologic upstaging among patients with nonmuscle-invasive bladder cancer, a study found.
Infectious endophthalmitis developed approximately 23 months after scleral fixation, a study shows.
In an update to treatment strategies for motor symptoms in early Parkinson disease, the American Academy of Neurology has reviewed the research on the benefits and risks of available medications.
Registry data show significant decreases in 14-day and 3-month case-fatality rates.
The sNDA submission is supported by data from a phase 3 trial that compared the efficacy and safety of fenfluramine with placebo in 263 patients aged 2 to 35 years with LGS.
The cumulative incidence of breast cancer recurrence was 8.5% at 15 years and 16.6% at 32 years.
People with familial hypercholesterolemia with COVID-19 risk endothelial dysfunction. Therapy should continue during the course of the virus.
Investigators assessed the association between diet quality and risk for and severity of COVID-19, as well as its relationship with socioeconomic deprivation.
Molnupiravir is an orally administered form of a ribonucleoside analogue that inhibits the replication of SARS-CoV-2.
In preclinical studies, CRV431 has been shown to reduce liver fibrosis and hepatocellular tumor burden.
The application could not be approved in its present form due to manufacturing deficiencies.
Researchers sought to determine whether red blood cell exchange transfusion may be beneficial for patients with sickle cell disease and COVID-19.
Using the Mayo Clinic’s COVID-19 Vaccine Registry, researchers were able to measure the incidence of myocarditis after patients received COVID-19 mRNA vaccination.
A team of investigators examined repetitive behavior exhibited among children later diagnosed with autism spectrum disorder.