HealthDay News — According to a study published in the American Journal of Physiology-Heart and Circulatory Physiology, resistance interval training (R-INT) has been associated with improved endothelial function, especially in those with type 2 diabetes (T2D).

Monique Francois, from the University of British Columbia Okanagan in Canada, and colleagues examined the effect of a single session of resistance- and cardio-based INT versus a time-matched control on endothelial function in 12 age-matched patients with T2D, 12 untrained and 11 trained adults. 

The authors assessed flow-mediated dilation of the brachial artery at baseline, as well as immediately, 1 hour and 2 hours after an acute bout of cardio interval training (C-INT), R-INT and seated control (CTL).

Continue Reading

The researchers found that in all groups, endothelial function was improved after R-INT and the effect was most robust in T2D where flow-mediated dilation was higher immediately, 1 hour and 2 hours after R-INT versus control (all P<.01). Compared with control, C-INT improved flow-mediated dilation at 1-hour post-exercise (P=.03).

“Our data indicate a potential therapeutic effect of R-INT on endothelial function in older adults with and without T2D,” the authors write. “The mechanisms underlying these effects warrant further investigation.”


Francois ME, et al. “Resistance-Based Interval Exercise Acutely Improves Endothelial Function In Type 2 Diabetes”. Am J Physiol Heart Circ Physiol. 2016 September 9. doi: 10.1152/ajpheart.00398.2016. [Epub ahead of print]

Related Articles