HealthDay News — According to a study published in Diabetes, Obesity and Metabolism, replacement of diet beverages (DBs) with water is associated with greater weight reduction and improvements in glucose metabolism in overweight and obese women with type 2 diabetes.

Ameneh Madjd, PharmD, from the University of Nottingham in the United Kingdom, and colleagues compared the effect of replacing DBs with water in patients with type 2 diabetes. 

During a 24-week weight-loss program, 81 overweight and obese women with type 2 diabetes were asked to substitute DBs for water or to continue drinking DBs 5 times per week after lunch.

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The researchers found that over the 24-week period, the water group had greater decreases in weight, body mass index, fasting plasma glucose, fasting insulin, homeostasis model assessment of insulin resistance and 2-hour postprandial glucose compared with the DB group. 

Over the study period there were no significant time × group interactions for waist circumference, lipid profiles and glycated hemoglobin within the groups.

“Replacement of DBs with water after the main meal in obese adult women with type 2 diabetes may lead to more weight reduction during a weight loss program,” the authors write.


Madjd A, et al. “Beneficial Effects Of Replacing Diet Beverages With Water On Type 2 Diabetic Obese Women Following A Hypo-Energetic Diet: A Randomized, 24-Week Clinical Trial”. Diabetes, Obesity and Metabolism. 2016. doi: 10.1111/dom.12793. [Epub ahead of print]

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