Combinatorial Therapies With Varenicline Most Effective for Smoking Cessation
In this study, researchers investigated how smoking cessation medicines compare with respect to their, clinical effectiveness, safety, and cost effectiveness.
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A New Year for COVID-19 and the Pandemic: Triumphs and Challenges
Dr Ryan Maves, CHEST COVID-19 Task Force Chair, talks about COVID-19-related triumphs of 2021, what clinicians can do now, and challenges for 2022.
Looking for Lifeguards: Community Connectors
It looks like any one of the dozen party supply stores found in this neck of the neighborhood. Pinatas, balloons, floral bouquets, and streamers adorn the door, inviting you to at least consider throwing a party. Outside, a colorful, though dented, food truck is parked flanked by a variety of vendors selling everything from blankets…
Voting Behaviors of US Physicians vs the General Population From 2000 to 2020
Researchers conducted a study that compared voter turnout between physicians and the general population for US elections held between 2000 and 2020.
Longer Time Spent Sitting During the COVID-19 Pandemic Linked With Depressive Symptoms
The aim of this study was to understand the relation between changes in behavior and mental health during the early phase of the first wave of the COVID-19 pandemic in the United States during April and May, 2020.
Symptomatic Gallstone Disease Following Bariatric Surgery May Be Prevented With Ursodeoxycholic Acid Prophylaxis
Investigators assessed the efficacy of ursodeoxycholic acid in preventing symptomatic gallstone disease among patients undergoing bariatric surgery.
COVID-19 and Moral Injury: a Mental Health Pandemic for Frontline Health Care Workers
Intervention strategies for health care workers experiencing COVID-19-related moral injury include health promotion, resilience training, and ongoing multilevel support.
Lithium Did Not Reduce Suicide-Related Events Among Veterans With a History of Suicidality
In this study, patients were stratified by condition and suicide history and randomized to receive 600 mg/d extended-release lithium carbonate or placebo in addition to usual care.
Are People With Asthma at Greater Risk for Severe COVID-19?
Clinicians initially thought that people with asthma would have worse COVID-19 outcomes, but does current evidence support this theory?
Comprehensive Hospice, Symptom Assessment Could Steer Patients Toward Appropriate Care Model
A large cohort study sought to determine the effects of hospice care type on management of end of life in terminally ill patients.
Oral vs IV Antibiotics for Pseudomonas aeruginosa Infection in Patients With Cystic Fibrosis
Researchers conducted a study to compare the effects of intravenous vs oral antibiotics therapy in patients with a pulmonary infection caused by Pseudomonas aeruginosa secondary to cystic fibrosis.
Gender Disparities in Mental Health Among Physician Parents Increased During the COVID-19 Pandemic
This study is the first to examine gender differences in work-family conflict and wellbeing in a cohort of physician parents before and during the COVID-19 pandemic.
Evidence Lacking for Effectiveness of Daily Thiamine to Reduce Symptoms of Fatigue in IBD
Investigators assessed the effects of 300 mg daily thiamine on maintaining levels of fatigue in patients with IBD previously receiving high-dose thiamine.
Efficacy, Safety of the Ad5-nCoV Vaccine for Protection Against COVID-19
Researchers conducted a study to determine the safety and efficacy of the Ad5-nCoV vaccine for protection against SARS-CoV-2 infection in adult patients.
Medical Practice Analysis: An Indispensable Prelude to Retirement
Physicians planning to retire need to establish their practice’s value and review factors affecting it.
Prucalopride Associated With Reduced Abdominal Bloating in Chronic Idiopathic Constipation
Investigators reviewed the effect of treatment with prucalopride on abdominal bloating and health-related quality of life in patients with chronic idiopathic constipation.
Could Lyme Disease Cause Alzheimer Disease or Lewy Body Dementia?
A team of researchers investigated whether credible evidence supporting a causal relationship between Lyme disease and Alzheimer disease or Lewy body dementia exists.
Single-Blind Placebo Run-In Periods Do Not Increase Antidepressant Trial Sensitivity
Researchers examined the association of the use of the placebo run-in period with the placebo response, drug response, and drug-placebo difference among randomized clinical trials of antidepressants.
High-Frequency Spinal Cord Stimulation Effectively Reduces Painful Diabetic Neuropathy
High-dose spinal cord stimulation was efficacious for the treatment of painful diabetic neuropathy.
Mind–Body Exercise Helps Bone Mineral Density in Lumbar Spine and Femoral Neck
Exercise slows bone loss and increases bone density in people at risk for osteoporosis, but which exercises are most effective are unclear. Investigators sought the answer.
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