HealthDay News — The Annals of Internal Medicine has published a new adult vaccine schedule from the US Centers for Disease Control and Prevention’s Advisory Committee on Immunization Practices.

One of the major changes is that the nasal influenza vaccine is no longer recommended, as studies have found it largely ineffective. 

Another update addresses the safety of influenza vaccination in patients with egg allergy. 

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The new guidance states that even patients who develop symptoms like swelling, lightheadedness or breathing difficulties may get either the inactivated influenza vaccine or recombinant influenza vaccine. 

However, they should receive the injection under supervision of a health care provider who is able to recognize and manage severe allergic conditions.

Regarding the human papillomavirus (HPV) vaccine for adolescents, the committee notes that young people who receive their first dose of the HPV vaccine before age 15 and the second dose at least 5 months later may be vaccinated in just 2 doses, instead of the 3 as was previously recommended.

Both the American Cancer Society and the CDC advisory committee still recommend 3 doses of the HPV vaccine for young adults who were not immunized as adolescents. The vaccine may be given to women through age 26 and men through age 21.

The new immunization schedule recommends that adults with HIV should receive a 2-dose series of serogroups A, C, W and Y meningococcal conjugate vaccine. The schedule also adds patients infected with the hepatitis C virus to the list of those with chronic liver disease who could benefit from a hepatitis B vaccine series. 

Others who should receive these injections are people with cirrhosis, fatty liver disease, alcoholic liver disease, autoimmune hepatitis and elevated levels of alanine aminotransferase or aspartate aminotransferase.


Kim DK, et al. “Recommended Immunization Schedule for Adults Aged 19 Years or Older, United States, 2017.” Ann Intern Med. 2017. 166: 209-219. doi: 10.7326/M16-2936

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