“Knowledge is power” is an old saying. Another cliché warns, “a little knowledge is a dangerous thing.” When it comes to getting inoculated against the human papillomavirus (HPV), it seems that neither saying is true. In fact, according to a study by a multidisciplinary University of Pennsylvania research team, knowledge may in fact be a meaningless thing.

A year-long study of over 360 adolescents who were considered to be ideal candidates to receive the HPV vaccine showed that neither increased parental nor adolescent knowledge about HPV or the vaccine resulted in higher rates of vaccination. That is, those with higher levels of knowledge were not more likely to obtain a vaccination for themselves or their daughters.

The study, reported in the journal Pediatrics, raises questions about traditional dogma related to using public service announcements and other educational efforts to increase knowledge about the vaccination.

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Researchers Jessica Fishman, PhD; Lynne Taylor, PhD; Patricia Kooker, MS; and Ian Frank, MD from the University of Pennsylvania’s Annenberg School for Communication and the Perelman School of Medicine surveyed a group of adolescents and parents of adolescents to determine their knowledge of HPV and the HPV vaccine. The study was funded in part by the Center of Excellence in Cancer Communication Research (CECCR) at the Annenberg School for Communication.

In addition to surveying participants, the researchers tracked whether vaccinations were received, via an analysis of clinical records kept through Philadelphia’s Kids Immunizations Database/Tracking System (KIDS). The results of the surveys showed that only about 14% of the adolescents were ultimately vaccinated.

“Knowledge was neither necessary nor sufficient. Although knowledge is often assumed to be key to increasing vaccination rates, it may be unwise to place so much promise on knowledge,” said Dr. Fishman, the study’s lead author. “Providers who reduce missed opportunities to offer vaccination, along with convenient and affordable vaccination may be very important. While the vaccination is shown to be effective, uptake remains very low in this high-risk population.”

The researchers stress that future studies should include additional populations. They also suggest that future studies should examine which modifiable factors predict those who vaccinate so that interventions can target those factors.

The study was directly funded by the Pennsylvania Department of Health (SAP 4100038712). Dr. Fishman is supported by the American Cancer Society (MRSG 115068).

The above story is reprinted from materials provided by Penn Medicine, via Newswise.

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