HealthDay News — According to a study published in JAMA Cardiology, people who regularly use electronic cigarettes may face an increased risk for cardiovascular disease.

All of the 23 e-cigarette users in the study were healthy and between the ages of 21 and 45, and had been vaping almost daily for a minimum of one year. 

None of the participants smoked tobacco cigarettes. All the e-cigarette users and nonusers had blood tests and heart rate variability testing.

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The researchers found that among e-cigarette users, heart rate variability was shifted toward increased sympathetic predominance, with a significantly increased low frequency to high frequency ratio.

In addition, low-density lipoprotein oxidizability, a measure of oxidative stress, was significantly increased among e-cigarette users.

“In this study, habitual e-cigarette use was associated with a shift in cardiac autonomic balance toward sympathetic predominance and increased oxidative stress, both associated with increased cardiovascular risk,” the authors write. “Further research into potential adverse health effects of electronic cigarettes is warranted.”


Moheimani RS, et al. “Increased Cardiac Sympathetic Activity and Oxidative Stress in Habitual Electronic Cigarette Users: Implications for Cardiovascular Risk.” JAMA Cardiol. 2017. doi:10.1001/jamacardio.2016.5303. [Epub ahead of print]

Bhatnagar A. “Are Electronic Cigarette Users at Increased Risk for Cardiovascular Disease?.”JAMA Cardiol. 2017. doi:10.1001/jamacardio.2016.5550. [Epub ahead of print]

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