Medicine

Treatment for Accelerating Postop Bowel Function Gets Fast Track Status

LB1148 is a broad-spectrum serine protease inhibitor designed to neutralize digestive enzymes and potentially reduce intestinal damage.

FDA: Prolia Use in Dialysis Patients May Cause Severe Hypocalcemia

According to a long-term safety study and a separate FDA internal study, Prolia had an increased risk of hypocalcemia in patients with advanced kidney disease on dialysis.

Vitamin D3 Does Not Improve Cardiovascular, Cancer Outcomes

The VITAL randomized clinical trial tested vitamin D and marine omega-3 fatty acid supplements in the primary prevention of cancer and cardiovascular disease.

New-Onset SVT Following Colonoscopy Bowel Prep Explored in Case Series

A significant percentage of affected patients were observed to have dilated atria and left ventricular hypertrophy.

Novel GI-Selective Therapy Gets Orphan Drug Designation for Pouchitis

The designation is supported by data from the 12-week, randomized, double-blind phase 2 FILLMORE trial.

FDA Authorizes Emergency Use of Kineret for Certain Hospitalized COVID-19 Patients

Kineret is an interleukin-1 receptor antagonist.

FDA Panel Votes on New Combination Therapy for Asthma

The vote was mixed when the data was reviewed for younger patients.

Certain Omicron Subvariants May Be Resistant to Bebtelovimab

Bebtelovimab is currently authorized for emergency use for the treatment of mild to moderate COVID-19 in adults and pediatric patients.

Study Reveals Pregnancy-Related Discrimination in Oncology Practice

Nearly a third of female oncologists surveyed said they experienced some form of discrimination during pregnancy.

Kidney Function Declines More Slowly With SGLT2 Inhibitor

Treatment with an SGLT2 inhibitor may help patients with CKD or type 2 diabetes better preserve their kidney function.

Empagliflozin Cuts Risk of Kidney Disease Progression, CV Death in CKD Patients

The EMPA-KIDNEY trial enrolled more than 6600 patients 18 years of age and older with CKD at risk of kidney disease progression.

CDC Releases Updated Guidance on Prescribing Opioid Pain Medication

The 2022 CDC Clinical Practice Guideline is intended to help clinicians weigh the benefits and risks of opioids and alternative pain treatments for outpatients.

Iron Deficiency Without Anemia Common in Peritoneal Dialysis Population

Iron deficiency associates with adverse outcomes in patients on peritoneal dialysis, regardless of anemia status.

Anemia Increases Dementia Risk in CKD

The association is revealed in a study of more 444,000 US veterans with new-onset chronic kidney disease.

Medication Administration Processes Often Interrupted in Post-Acute Care Setting

Study finds that medication administration processes (MAPs) are frequently interrupted and these disruptions may create an opportunity for patient harm.

TransCon PTH Gets Priority Review for Hypoparathyroidism

TransCon PTH is an investigational once-daily long-acting prodrug of parathyroid hormone (PTH[1-34]) designed to restore physiologic levels of PTH for 24 hours each day.

Vemlidy Approved for Pediatric Patients With Chronic HBV Infection

The approval was supported by data from a phase 2 trial that included 70 patients aged 12 to less than 18 years with chronic HBV infection.

Stable Clinical Outcomes Seen With Octocog Alfa Prophylaxis in Hemophilia A

Researchers sought to determine whether prophylaxis with octocog alfa would lead to stable bleeding rates in patients with hemophilia A.

Wearable Medical Monitoring Devices: The Innovation Continues

An ultrasound monitor that can stick to the skin and provides sharp images of blood vessels and internal organs is among the latest medical remote monitoring technologies under development.

Finerenone May Protect Against Pneumonia and COVID-19

Finerenone, a mineralocorticoid receptor antagonist, may exert anti-inflammatory and anti-fibrotic effects, according to investigators.