Medicine

Addressing Sleep Disturbances of Parkinson Disease

Sleep disturbances may affect 40% to 90% of patients with PD, and a 2020 study found that about half of patients with PD had multiple sleep disorders.

Increased Patient Satisfaction With Extended Release Buprenorphine for the Treatment of Opioid Use Disorder

If immediate-release and extended-release formulations of buprenorphine are similarly efficacious to treat opioid use disorder, is one superior?

Many Individuals With Serious Mental Illness Successfully Quit Smoking With a Scalable, Multicomponent Intervention Program

The study authors sought to determine if a brief, multicomponent, sustained care smoking cessation intervention tailored to individuals with severe mental illness can facilitate treatment engagement and abstinence following hospital discharge.

Novel Biosensor Aids in the Discovery of a Psychedelic Drug Without Hallucinogenic Effects

To better understand the conformational effects of psychedelic compounds, researchers developed psychLight, a genetically encoded biosensor that generates fluorescence in 5-HT2AR.

COVID-19 Lockdown: Melanomas Still Diagnosed but Follow-Up Decreased

Italian researchers retrospectively compared dermatologic and surgical activity in their melanoma unit from February to May, 2020, with data from the same period in 2019.

Atorvastatin With Sodium Valproate Can Reduce Migraine Attacks and Pain Severity

Atorvastatin may have augmentative effects with sodium valproate in the reduction of migraines with aura.

Combination Immunotherapy Effective for Patients With Melanoma and Asymptomatic Brain Metastases

The combination of nivolumab with ipilimumab is an effective treatment option for patients with advanced melanoma with asymptomatic brain metastases

Intralesional Vitamin D Injections Can Significantly Reduce Keloid Thickness

The efficacy of intralesional injection of vitamin D in the treatment of keloids, both clinically and ultrasonically, was evaluated.

OrthoDx: Cyst on Index Finger

A 75-year-old woman presents with a cyst on her right index finger that has been present for 3 weeks. What is the best treatment option?

Epidermolysis Bullosa: Treatment Challenges and Emerging Developments

Even though it is often thought of as a skin condition, many forms of epidermolysis bullosa are truly multisystem disorders, which makes coordinating the care complex.

Case Report: Scurvy in an Incarcerated Man

An ill-appearing patient presents with a complaint of lower extremity rash, dyspnea on exertion, fatigue, and orthostasis.

Approach Bias Retraining With Virtual Reality Technology Reduces Smoking

The researchers combined virtual reality with Approach Bias Modification to determine if this would improve smokers’ motivation to quit smoking and reduce the number of dropouts from smoking cessation programs.

Expert Q&A: MAPS and Psychedelic-Assisted Psychotherapy

After decades of limited research and legal roadblocks to medical and recreational use, psychedelic drugs are rapidly remerging as treatments of interest in psychiatry. We interviewed two experts in the field.

Electronic Nicotine Delivery System May Reduce Toxicant Exposure, Cigarette Consumption

People using electronic nicotine delivery systems with cigarette-like nicotine delivery may reduce their exposure to a tobacco-specific carcinogen metabolite, even with concurrent smoking.

Breast Implant-Associated Anaplastic Large Cell Lymphoma: An Update

The occurrence rate of BIA-ALCL following breast augmentation with textured implants is variable, with the reported lifetime risk ranging from 1 in 355 to 1 in 86,029 patients.

G-POEM Is Safe, Modestly Effective for Refractory Gastroparesis

Investigators studied the safety and efficacy of gastric per-oral endoscopic myotomy in patients with refractory gastroparesis.

Impact of the COVID-19 Pandemic on Adolescent Mental Health

Even before the COVID-19 pandemic began, concerning mental health trends and major treatment gaps were noted among adolescents. We spoke with Cécile Rousseau, MD, researcher, psychiatrist, and professor in the division of social and transcultural psychiatry at McGill University in Montreal, Canada about the impact of the COVID-19 pandemic on adolescent mental health.

American Lung Association Report Shows 40% of US Regularly Breathes Polluted Air

The American Lung Association’s 22nd annual “State of the Air” report shows that approximately 40% of Americans breathe polluted air on a regular basis.

Clinical Challenge: Elbow Pain and Numbness in Fingers

A 40-year-old man reports pain in his right elbow and numbness in his right pinky and ring fingers. What is your diagnosis?

Botulinum Toxin Use Associated With Improvements in Depression

Can use of botulinum toxin injection improve severity in patients with depression?