Medicine

What Clinicians Need to Know About Oral Antivirals for COVID-19: An Expert Q&A

In this Q&A, Erica Johnson, MD, provides insight into the new oral antiviral medications that may soon be approved for the treatment of COVID-19.

Red Blood Cell Exchange Transfusion May Be Beneficial in Patients With Sickle Cell Disease and COVID-19

Researchers sought to determine whether red blood cell exchange transfusion may be beneficial for patients with sickle cell disease and COVID-19.

Diet Supplementation With Artichoke Extract May Effectively Decrease Liver Enzymes Among Some Patients

Investigators assessed the effects of dietary artichoke supplementation on levels of liver enzymes.

CRC Screening Rates Increase During Past Decade While Remaining Suboptimal

Investigators assessed rates of colorectal cancer screening participation in the time periods before and after introduction of multi-target stool DNA tests.

Expert Panel Sees Challenges With Federally Mandated Opioid Prescriber Education

During the workshop, speakers and panelists reviewed past programs that were put into place to reduce opioid prescribing, as well as trends in opioid prescribing and overdose deaths.

Droplet-Based Digital PCR May Be Effective for Prenatal Alpha-Thalassemia Detection

Researchers sought to determine whether a droplet digital PCR would be effective for noninvasive prenatal diagnosis of thalassemia.

Effect of a National Human Papillomavirus Immunization Program on Cervical Cancer Incidence

Researchers conducted a study to determine the effect of a national human papillomavirus (HPV) immunization program on the incidence of cervical cancer and grade 3 cervical intraepithelial neoplasia among young women in England.

Bile Reflux: Clinical Considerations

Biliary reflux is difficult, yet important, to distinguish from acid reflux, in order to ensure proper treatment for these patients.

Metformin and Sulfonylurea Use in People With Type 2 Diabetes and COVID-19

COVID-19 can cause additional complications and even death in people with a pre-existing conditions like type 2 diabetes. Researchers studied whether the medications people with type 2 diabetes often take were associated with a risk of dying from the virus.

The Pros and Cons of Medical Cannabis: Current Evidence

The widespread use of cannabis and the public perception that it is harmless make screening and patient counseling a priority.

Preparing for COVID-19 Vaccinations in Children

To answer the many questions regarding the roll out, risk and benefits, and timing of COVID-19 vaccine administration in children aged 5 to 11 years, The Clinical Advisor interviewed Mary Koslap-Petraco, DNP, PPCNP-BC, CPNP, FAANP, a pediatric nurse practitioner and owner of Pediatric Nurse Practitioner House Calls.

The Importance of Equity in Addressing Disparities in Health Care

Equality assures that everyone receives the same thing, but equity assures that everyone gets what they need.

RBX2660 Reduces Recurrent C difficile Infections in Patients With Comorbid Conditions

Researchers evaluated the safety and efficacy of the investigational, microbiota-based, live biotherapeutic RBX2660 for treatment of recurrent C difficile infection.

Pathogenic Effects of Probiotics in Children With Acute Gastroenteritis

Researchers conducted a study that compared the effects of probiotics vs placebo for the treatment of children with diarrhea secondary to acute gastroenteritis.

Nasal Spray With Iota-Carrageenan Decreases Risk for COVID-19 in Exposed Healthcare Workers

Investigators conducted a study to determine whether iota-carrageenan nasal spray decreases the risk for SARS-CoV-2 infection among health care workers managing patients with COVID-19.

Oral and Topical Antifungals Beneficial for Dupilumab Facial Redness in Atopic Dermatitis

A novel study reports the positive response to oral and topical antifungals for patients with atopic dermatitis (AD) treated with dupilumab who developed facial redness.

NASEM: Building Parents’ Confidence in COVID-19 Vaccines

Having the tough conversations. NASEM offers recommendations for communicating with parents of young children about COVID-19 vaccines.

Brodalumab Effective for Psoriasis Treatment After Other IL-17 RA Failure

The short- and long-term effectiveness of brodalumab in patients with psoriasis in whom treatment with IL-17A inhibitors has failed is examined.

Risk Factors Associated With Vertical Transmission in Mothers With HIV Infection

Researchers sought to assess whether there is an association between maternal HIV drug resistance and an increased risk for vertical transmission and to describe the dynamics of drug resistance in infants with HIV infection.

Clinical Efficacy, Safety of Janus Kinase Inhibitors in Patients Hospitalized With COVID-19

Investigators conducted a meta-analysis of 3 randomized controlled trials that compared the clinical safety and efficacy of janus kinase inhibitors with placebo or standard care for the treatment of patients with COVID-19.