Carlene Majorino

All articles by Carlene Majorino

Evidence suggests 19% to 40% of those who are aPL-positive and 42% to 80% of those with primary APS have CD.3 In addition, 2.5% of patients with APS have multi-infarct dementia resulting from recurrent ischemic events.6 Because cognitive deficits are also observed in patients with APS who have no evidence of neurologic involvement, the mechanism of CD in APS is likely multifactorial.3,7 Animal studies have also observed CD in APS models with no evidence of ischemic lesions, and findings suggest that aPL antibodies may affect brain tissue directly.3,7 The spectrum of CD varies from mild to severe, but deficits in attention, concentration, processing speed, executive function, and memory loss are common.3 Patients with APS-related dementia may have impaired judgment, language impairment, and memory loss that can be severe enough to arouse suspicion of Alzheimer disease.6,8 Empirical observation has shown that anticoagulation therapy improves memory loss in some patients.8 Image Credit: ISM/SOVEREIGN

News

Dementia Associated With RA, But Mitigation Depends on Lifestyle

Carlene Majorino

August 6, 2021

We spoke with 2 rheumatologists with recent research on dementia and RA who believe that exercise, well-being, and antiinflammatory drugs are crucial to treatment and prevention.

News

Q&A: Inhalants Other Than Personal Smoking and Rheumatoid Arthritis

Carlene Majorino

June 18, 2021

Jeffrey Sparks, MD, MMSc, says it’s difficult to single out environmental risk factors for RA because of the intersectional nature of patients’ conditions and exposures.

COVID mask doctor patient scalp skin exam

News

Systemic, Biologic Psoriasis Treatment and Low COVID-19 Infection Rate

Carlene Majorino

June 7, 2021

Anne-Claire Fougerousse, MD, elaborates on a recent study regarding psoriasis, SBTs, and COVID-19.

News

Sunlamp Use Linked to Uveal Melanoma Risk

Carlene Majorino

May 7, 2021

Researchers found the association after reviewing 1753 patients from 5 studies.

Medicine

Triaging Emergency Eye Patients Remotely and With Success

Carlene Majorino

April 15, 2021

Jordan Deaner, MD, Duke University Eye Center and Cecilia Koetting, OD, FAAO, of Virginia Eye Consultants, offer advice on remote triaging and how to spot an ocular emergency.

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Carlene Majorino

All articles by Carlene Majorino

Dementia Associated With RA, But Mitigation Depends on Lifestyle

Q&A: Inhalants Other Than Personal Smoking and Rheumatoid Arthritis

Systemic, Biologic Psoriasis Treatment and Low COVID-19 Infection Rate

Sunlamp Use Linked to Uveal Melanoma Risk

Triaging Emergency Eye Patients Remotely and With Success

Adolescents Planning School Attacks Motivated by Grievances, Bullying