Inosine Fails to Slow Early Parkinson Disease Progression in Phase 3 Trial
Researchers assessed the impact of oral inosine, a metabolic precursor of urate, on disease progression in patients with early Parkinson disease.
All articles by Amit Akirov, MD
Treatment Response to Zolpidem in Patients With Insomnia: The Importance of Priming
Researchers assessed whether zolpidem (priming) is required for partial reinforcement or whether intermittent dosing with placebos can be effective for acute and extended treatment for patients with chronic insomnia.
Does Anakinra Have a Role in the Treatment of Severe COVID-19?
Authors of a commentary assessed the role of IL-1 receptor antagonism, specifically anakinra, in the treatment of patients with severe COVID-19.
FIREFISH Trial Shows Risdiplam Benefits in Infants With Type 1 Spinal Muscular Atrophy
Researchers evaluated the safety and efficacy of risdiplam in infants with type 1 spinal muscular atrophy compared with historical cohorts.
Primary Central Nervous System Vasculitis: From Diagnosis to Management
Primary central nervous system vasculitis is an important but rare differential diagnosis in daily neurological practice, warranting the need of a step by step approach.
Outcomes of a Neurology Career Development Program for Underrepresented Minorities and People with Disabilities
A neurology career advancement program for people underrepresented in medicine may help early career individuals enter and remain in mainstream neurologic research and academic neurology.
Novel Risk Stratification Tool Identifies Patients at High Risk for Inpatient Gout Flare
Researchers developed and validated a gout flare risk stratification tool for patients with gout who were hospitalized for nongout conditions.
New Position Statement on the Importance of Sleep to Health and Well-Being
The American Academy of Sleep Medicine provided a position statement on the importance of sleep in health and several objectives to improve health, productivity, and well-being.
Post-Traumatic Coma Prognosis is Difficult to Predict
Bianciardi and colleagues investigated the patterns of microbleeds associated with post-traumatic coma and the recovery of consciousness in young comatose patients.
Atorvastatin With Sodium Valproate Can Reduce Migraine Attacks and Pain Severity
Atorvastatin may have augmentative effects with sodium valproate in the reduction of migraines with aura.
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